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Asymptomatic idiopathic intracranial hypertension in children
Authors:Bassan H  Berkner L  Stolovitch C  Kesler A
Affiliation:Pediatric Neurology Unit, 'Dana' Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Abstract:Objective – To define characteristics of pediatric asymptomatic idiopathic intracranial hypertension (IIH). Patients and methods – We retrospectively reviewed our Neuro‐Ophthalmology database (2000–2006) for all cases of symptomatic and asymptomatic pediatric IIH. Results – Out of 45 IIH cases, 14 (31.1%) were asymptomatic (incidental examination). When compared with children with symptomatic IIH, asymptomatic cases were younger [5.6 (1.8–15) vs 11.0 (5–17) years, P = 0.007], had lower percentage of obesity (14.3% vs 48.4%, P = 0.046), and had male predominance (71.4% vs 38.7%, P = 0.06). Asymptomatic cases required shorter duration of acetazolamide treatment [3 (0–8), vs 6 (0–20) months, P = 0.021], and resulted in complete resolution of swollen discs. Conclusions – We speculate that asymptomatic IIH may be more common in young children and could represent a milder form or a presymptomatic phase before evolving into classic symptomatic IIH. Further studies to assess the clinical significance of asymptomatic IIH are warranted.
Keywords:acetazolamide  asymptomatic  idiopathic intracranial hypertension  lumbar puncture  obesity  pseudotumor cerebri
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