| TC方案化疗联合同期放疗治疗中晚期鼻咽癌临床观察 |
| |
| 引用本文： | 邹雨荷,田鲜艳,何景扬,王羽,张钦华.TC方案化疗联合同期放疗治疗中晚期鼻咽癌临床观察[J].现代肿瘤医学,2011,19(1):29-31. |
| |
| 作者姓名： | 邹雨荷 田鲜艳 何景扬 王羽 张钦华 |
| |
| 作者单位： | 广东省江门市中心医院肿瘤科,广东,江门,529030 |
| |
| 摘 要： | 目的:观察紫杉醇+卡铂同期放化疗治疗中晚期鼻咽癌的疗效及不良反应。方法:86例确诊为中晚期鼻咽癌患者随机分为治疗组TC同期放化疗组42例和对照组PF同期放化疗组44例,TC组在放射治疗的第1、4周给予2个周期紫杉醇+卡铂方案化疗(紫杉醇135mg/m2d1,卡铂AUC=6 d1;PF组在放射治疗的第1、4周给予2个周期5-FU+顺铂方案化疗(顺铂20mg/m2iv d1-5,5-FU 500 mg/m2)。结果:TC组1、3年生存率分别为100%(42/42)、73.8%(36/50),PF组91.0%(43/44)、78.0%(35/44)(P>0.05);TC组口腔黏膜损伤、消化道反应明显低于PF组(P<0.05)。两组局部控制率、远处转移率及骨髓功能抑制无统计学差异(P>0.05)。结论:紫杉醇+卡铂同步放化疗治疗局部晚期鼻咽癌耐受性好,疗效满意。
|
| 关 键 词： | 鼻咽癌 同步放化疗 紫杉醇 卡铂 |
A clinical research of docetaxel plus carboplatin with concurrent radiotherapy in the treatment of locally advanced nasopharyngeal carcinoma |
| |
| ZOU Yu-he,TIAN Xian-yan,HE Jing yang,WANG Yu,ZHANG Qin-hua.A clinical research of docetaxel plus carboplatin with concurrent radiotherapy in the treatment of locally advanced nasopharyngeal carcinoma[J].Journal of Modern Oncology,2011,19(1):29-31. |
| |
| Authors: | ZOU Yu-he TIAN Xian-yan HE Jing yang WANG Yu ZHANG Qin-hua |
| |
| Institution: | ZOU Yu-he,TIAN Xian-yan,HE Jing yang,WANG Yu,ZHANG Qin-hua Department of oncology,the Central Hospitol of Jiangmen city,guangdong 529070,China. |
| |
| Abstract: | Objective:To evaluate the effect and toxicity of docetaxel plus carboplatin with concurrent radiotherapy in the treatment of locally advanced nasopharyngeal carcinoma.Methods:Total of 86 cases with locally advanced nasopharyngeal carcinoma(stage III and IVa)were randomized into 2 groups.Group TC(n=42) received radiotherapy with docetaxel plus carboplatin(docetaxel 135mg/m2 d1,carboplatin AUC=6 d1).Group PF(n=44)received cisplatin 20mg/ m2 iv d1-5,5-FU 500 mg/ m2 iv d1-5 at the 1st and 4th week and received ... |
| |
| Keywords: | nasopharyngeal carcinoma concurrent radiochemotherapy carboplatin docetaxel |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
