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与食管癌5-FU化疗效果相关分子标记的研究进展
引用本文:严爱婷,钱晓萍,刘宝瑞. 与食管癌5-FU化疗效果相关分子标记的研究进展[J]. 现代肿瘤医学, 2011, 19(1): 166-169. DOI: 10.3969/j.issn.1672-4992.2011.01.062
作者姓名:严爱婷  钱晓萍  刘宝瑞
作者单位:1. 南京医科大学鼓楼临床医学院肿瘤中心,江苏,南京,210008
2. 南京医科大学鼓楼临床医学院肿瘤中心,江苏,南京,210008;南京大学医学院附属鼓楼医院肿瘤中心,江苏,南京,210008
基金项目:南京市科技局国际合作项目
摘    要:不同个体的食管癌对氟尿嘧啶(Fluorouracil,5-FU)药物疗效存在差异。药物遗传学和药物基因组学的快速发展,使得分子标记指导下的食管癌个体化化疗成为可能,本文对食管癌5-FU疗效预测相关分子标记作一综述。

关 键 词:5-FU  食管癌  分子标记

Researc progress on molecular markers of esophageal canccer treated by 5-FU
YAN Ai-ting,QIAN Xiao-ping,LIU Bao-rui. Researc progress on molecular markers of esophageal canccer treated by 5-FU[J]. Journal of Modern Oncology, 2011, 19(1): 166-169. DOI: 10.3969/j.issn.1672-4992.2011.01.062
Authors:YAN Ai-ting  QIAN Xiao-ping  LIU Bao-rui
Affiliation:1,21Department of Onology,Nasnjing Drum Tower Hospital Clinical College of Nanjing Medical University,Nanjing 210008,China;2Department of Onology,Nasnjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,China.
Abstract:Persons suffering from esophageal cancer have different therapeutic effect treated by 5-FU.With the rapid development of pharmacogenetics and pharmacogenomics,individualized chemotherapy for esophageal cancer is possible.This paper will make a review on the effect of esophageal cancer-5-FU-related molecular markers.
Keywords:5-FU
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