妊娠高血压疾病肾段动脉血流动力学的变化

目的探讨妊娠高血压疾病不同分期与孕妇肾段动脉(SRA)血流动力学变化的相关性。方法应用彩色多普勒超声检测260例妊娠高血压孕妇SRA搏动指数(PI)、阻力指数(RI)及收缩期峰值与舒张末期最大流速之比(S/D),与300例正常孕妇(对照组)做对照分析。结果⑴妊娠高血压疾病(轻度妊高征)组SRAPI、RI和S/D值;⑵轻度子痫前期组SRAPI、RI和S/D值较对照组轻度升高,但差异无统计学意义(P>0.05);⑶重度子痫前期组SRAPI、RI和S/D值较对照组及轻度妊高征组、轻度子痫前期组均明显升高,具有显著性差异(P<0.01)。结论⑴SRAPI、RI和S/D值不宜作为早期筛查妊娠高血压疾病的参考指标;⑵彩超检测重度子痫前期孕妇SRAPI、RI和S/D值,可作为判断病情、观察疗效的敏感指标。

Hypertensive Disorders of Pregnancy Renal Artery Hemodynamics Hange

OBJECTIVE To investigate the different stages of pregnancy-induced hypertension in pregnant women with renal disease associated with renal segmental arteries（SRA）hemodynamic changes.METHODS 260 patients were measured with color doppler ultrasound of pregnant women with hypertensive disorder of pregnancy SRA pulsatility index（PI）,resistance index（RI） and maximum peak systolic and end diastolic velocity ratio（S/D）,and 300 normal pregnant women were compared as control group.RESULTS ⑴The group of hypertensive disorders of pregnancy（mild PIH） SRAPI,RI and S/D＇s value;⑵The group of mild preeclampsia（moderate PIH）SRAPI,RI,S/D＇s value is slightly higher than the control group,but the difference was not statistically significant（P〉0.05）;⑶The group of severe preeclampsia SRA PI,RI and S/D values than the control group and the mild and moderate PIH group were significantly higher,the difference was significant（P〈0.01）.CONCLUSION ⑴ SRAPI,RI and S/D＇s value of early screening should not be used as reference for hypertensive disorders of pregnancy;⑵Color Doppler detection of pregnant women with severe preeclampsia SRAPI,RI and S/D＇s value could be used sensitive indicators to determine the disease effects and to observe therapeutic effect.