| 血管内皮细胞上清液对口腔颊黏膜成纤维细胞增殖活性的影响 |
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| 引用本文： | 李明,彭解英,庞丹琳. 血管内皮细胞上清液对口腔颊黏膜成纤维细胞增殖活性的影响[J]. 临床口腔医学杂志, 2010, 26(2): 89-91 |
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| 作者姓名： | 李明 彭解英 庞丹琳 |
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| 作者单位： | 中南大学湘雅医院口腔科,湖南,长沙,410078 |
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| 基金项目： | 湖南省科技厅社会发展基金资助项目(02SSY3052) |
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| 摘 要： | 目的：观察血管内皮细胞上清液（ECS）对正常人口腔颊黏膜成纤维细胞（NM-FB）增殖活性的影响。方法：收集不同时间点、并配成不同比例的ECS干预NM-FB。结果：ECS12h能促进NM-FB的增殖,随着时间延长ECS促增殖能力逐渐增强,ECS48h促FB增殖能力达到最大（P〈0.05）;ECS/（ECS＋RPMI-1640）比值为1/4时可促NM-FB增殖,ECS稀释倍数越小,NM-FB的增殖率越高（P〈0.05）。ECS能促进FB的增殖,存在时效和量效依赖关系。结论：血管内皮细胞能通过分泌某些介质影响口腔颊黏膜成纤维细胞的生物学活性。
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| 关 键 词： | 口腔黏膜下纤维性变 成纤维细胞 血管内皮细胞 |
Influence of supernatant from endothelial cells on the flbroblasts' bioactivity |
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| LI Ming,PENG Jie-ying,PANG Dan-lin. Influence of supernatant from endothelial cells on the flbroblasts' bioactivity[J]. Journal of Clinical Stomatology, 2010, 26(2): 89-91 |
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| Authors: | LI Ming PENG Jie-ying PANG Dan-lin |
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| Affiliation: | LI Ming,PENG Jie-ying,PANG Dan-lin.Department of Stomatology,Xiangya Hospital,Central South University,Hunan Changsha 410078,China |
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| Abstract: | Objective:To observe the influence of supernatant from endothelial cells(ECS)on the fibroblasts('NMFB)proliferation.Method:The ECS was collected at different time and mixed at different proportion to intervene NM-FB.Result:ECS12h could promote the NM-FB's proliferation,the promotion ability would be more strong along with the time and ECS48h would be the most(P < 0.05).The proportion of ECS/(ECS + RPMI-1640)to be 1/4 could promote the NM-FB's proliferation,the promotion ability would be more strong along wi... |
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| Keywords: | oral submucous fibrosis fibroblast endothelial cell |
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