| 可调压式细胞培育箱的研制 |
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| 引用本文： | 段小红,毛勇,张春宝,侯晋,汪卫国,施昭云,施纪泽.可调压式细胞培育箱的研制[J].生物医学工程学杂志,2005,22(6):1253-1255. |
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| 作者姓名： | 段小红 毛勇 张春宝 侯晋 汪卫国 施昭云 施纪泽 |
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| 作者单位： | 1. 第四军医大学,口腔医学院,西安,710032
2. 西安世纪测控技术研究所,西安,710049 |
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| 基金项目： | 国家自然科学基金资助项目(30100211) |
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| 摘 要： | 为研究离体培养细胞在静压力作用时的生长行为,研制了可调压式细胞培育箱。本装置包括持续性加压系统、间歇性加压系统、静压力控制测量系统、变形测量显示系统等。该系统不仅能模拟出细胞在密封培养箱内所承受的静压力效果,也可模拟出牵张力的力学作用效果,对研究细胞的应力生长关系十分有用。
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| 关 键 词： | 细胞培养 静压力 牵张力 |
| 收稿时间： | 2003-09-10 |
| 修稿时间： | 2003-09-102004-02-10 |
A Hydrostatic Compression Device Capable of Generating both Intermittent Compressive Forces and Continuous Compressive Forces |
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| Duan Xiaohong,Mao Yong,Zhang Chunbao,Hou Jin,Wang Weiguo,Shi Zhaoyun,Shi Jize.A Hydrostatic Compression Device Capable of Generating both Intermittent Compressive Forces and Continuous Compressive Forces[J].Journal of Biomedical Engineering,2005,22(6):1253-1255. |
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| Authors: | Duan Xiaohong Mao Yong Zhang Chunbao Hou Jin Wang Weiguo Shi Zhaoyun Shi Jize |
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| Institution: | Department of Oral Biology, Stomatological College, The Fourth Military Medical University, Xi'an 710032, China. |
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| Abstract: | A hydrostatic compression device has been designed to study the effects of intermittent or continuous compressive forces on cells by trying to mimic in vivo forces.The model system is composed of two pistons that deliver and release compressed air under control of a motor to form an enclosed tissue culture chamber housing numerous tissues culture dishes.The continuous compressive forces and intermittent compressive forces are within 100~300 KPa and 0~30 KPa respectively.The compressive force is uniform in the system and can also result in the generation of shear forces along the interface between the cells and culture substratum,so the hydrostatic compression device can be used to study the characteristics of in vitro cells loading models. |
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| Keywords: | Cell culture Hydrostatic compressive force Shear forces/strain |
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