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Camptothecin analogues with enhanced antitumor activity at acidic pH
Authors:David J. Adams  Mark W. Dewhirst  James L. Flowers  Michael P. Gamcsik  O. Michael Colvin  Govindarajan Manikumar  Mansukh C. Wani  Monroe E. Wall
Affiliation:(1) Department of Medicine, Duke University, Durham, NC 27710, USA, US;(2) Department of Radiation Oncology, Duke University, Durham, NC 27710, USA, US;(3) Research Triangle Institute, Research Triangle Park, NC 27709, USA, US
Abstract:
Keywords:Camptothecin  pH  Glutathione  In vitro screens  Drug development
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