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CA125在鉴别卵巢原发性癌和胃肠道转移性癌中的作用
引用本文:杨文涛,张廷,范建玄,施达仁. CA125在鉴别卵巢原发性癌和胃肠道转移性癌中的作用[J]. 中华妇产科杂志, 2001, 36(5): 302-303,T001
作者姓名:杨文涛  张廷  范建玄  施达仁
作者单位:1. 复旦大学医学院附属肿瘤医院病理科
2. 复旦大学医学院附属肿瘤医院妇科
摘    要:目的 CA12 5在鉴别卵巢原发性癌和来源于胃肠道的卵巢转移性癌中的价值。方法 采用免疫组织化学伊文生 (Envision) 2步法 ,对 33例卵巢原发性癌、5 0例卵巢转移性癌 (原发灶在胃肠道 )进行了CA12 5检测。结果  33例卵巢原发性癌CA12 5阳性率为 84 5 % ,5 0例卵巢转移性癌CA12 5阳性率为 4 0 % ,两者比较 ,差异有极显著性 (P <0 0 0 1)。结论 CA12 5的测定对鉴别卵巢原发性癌和来源于胃肠道的卵巢转移性癌有重要意义

关 键 词:CA-125抗原 卵巢肿瘤 肿瘤转移 鉴别诊断 胃肠道转移性肿瘤

The role of CA125 in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract
YANG Wentao ,ZHANG Tingqiu,FAN Jianxuan,et al. The role of CA125 in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract[J]. Chinese Journal of Obstetrics and Gynecology, 2001, 36(5): 302-303,T001
Authors:YANG Wentao   ZHANG Tingqiu  FAN Jianxuan  et al
Affiliation:YANG Wentao *,ZHANG Tingqiu,FAN Jianxuan,et al *Department of Pathology,Cancer Hospital,Shanghai Medical University,Shanghai 200032,China
Abstract:Objective To assess the role of CA 125 monoclonal antibody in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract Methods Immunohistochemical study using CA 125 monoclonal antibody was performed on 33 primary ovarian cancer and 50 metastatic ovarian cancer of gastrointestinal origin Results The positivity of CA 125 was 84 5% in 33 cases of primary ovarian carcinoma, while in 50 metastatic ovarian carcinoma cases, only 4 0% was CA 125 positive The positivity of CA 125 was significantly higher in primary ovarian carcinoma than metastatic ovarian carcinoma ( P <0 001) Conclusion CA 125 monoclonal antibody is useful in the differential diagnosis of ovarian carcinoma
Keywords:CA 125 antigen  Ovarian neoplasms  Neoplasm metastasis  Diagnosis   differential  Gastrointestinal neoplasms
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