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一例皮肤泛发性球毛壳菌病临床分析
引用本文:王盛华,戴文丽,路麒,暴芳芳,李晓莹.一例皮肤泛发性球毛壳菌病临床分析[J].中国麻风皮肤病杂志,2021,37(6):352-355.
作者姓名:王盛华  戴文丽  路麒  暴芳芳  李晓莹
作者单位:1山东第一医科大学附属省立医院临床医学检验部,山东济南,250021; 2山东第一医科大学附属省立医院皮肤科,山东济南,250021; 3山东第一医科大学附属皮肤病医院(山东省皮肤病医院,山东省皮肤病性病防治研究所),山东济南,250022
摘    要:患者,男,55岁.全身红色结节伴剧痒6个月.皮损真菌荧光染色直接镜检及真菌培养均阳性.提取培养物DNA进行PCR扩增和测序,鉴定为球毛壳菌.给予伊曲康唑、金菌灵及黄芪颗粒口服,联苯苄唑乳膏外用,治疗2个月病情逐渐好转.经文献检索,确认本病例是我国报道的第4例球毛壳菌病.

关 键 词:球毛壳菌  毛壳菌病

Clinical analysis of one case with Chaetomium globosum cutaneous infection
WANG Shenghua,DAI Wenli,LU Qi,BAO Fangfang,LI Xiaoying.Clinical analysis of one case with Chaetomium globosum cutaneous infection[J].China Journal of Leprosy and Skin Diseases,2021,37(6):352-355.
Authors:WANG Shenghua  DAI Wenli  LU Qi  BAO Fangfang  LI Xiaoying
Institution:1 Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China;   2 Department of Dermatology, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan 250021, China;   3 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
Abstract:A 55-year-old man presented with systemic red nodules and intense itching for 6 months. Microscopic examination and fungal culture of the lesions were positive. DNA extracted from the culture was sequenced and identified as Chaetomium globosum. The patient was treated with oral itraconazole, Jinjunling and Huangqi granules and topical bifonazole cream. The patient was improved after two months of treatment. This case is the fourth chaetomycosis caused by Chaetomium globosum reported in China.
Keywords:Chaetomium globosum  chaetomycosis  
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