大鼠头部副交感神经节脑啡肽神经元的分布及其出生后变化

用间接免疫荧光法观察了不同年龄组大鼠睫状神经节、翼腭神经节和耳神经节内甲硫氨酸脑啡肽免疫反应阳性神经元的分布,发现出生后1天上述神经节内脑啡肽神经元百分比最高,分别为43.3%、43.6%和33.0%.出生后4周内脑啡肽神经元数量有明显的变化,在睫状神经节和翼腭神经节为先下降,继而上升,在耳神经节只呈下降趋势.成年至老年脑啡肽神经元数量无明显变化.在成年组,睫状神经节脑啡肽元数量最多(38.9%),翼腭神经节次之(34.0%),耳神经节最少(30.9%).脑啡肽广泛分布于头部副感神经节,提示它们可能参与头面部内脏运动调节.

DISTRIBUTION AND POSTNATAL ONTOGENESIS OF ENK-IR NEURONS IN RAT CRANIAL PARASYMPATHETIC GANGLION

The distribution of enkephalin-immunoreactive(ENK-IR) neurons was observed in the ciliary, pterygopalatine and otic ganglions of different age-bracket rats by indirect immunofluorescence method. It was found that the number of ENK-IR neurons reached its maximal at the first postnatal day(43.3% , 43. 6% and 33. 0% , for the ciliary, pterygopalatine and otic ganglions respectively). The number of ENK-IR neurons varied obviously at 4th postnatal week, first decreasing and then increasing for the ciliary and peteygopalatine ganglions; and simply decreasing for the otic ganglion. There was no significant differance between adult and old rats in the number of ENK-IR neurons. In adult rats, the number of ENK-IR neurons was greatest in the ciliary ganglion(38.9%), the number of the peteygopalatine ganglion was the next (34.0 %), and the number of ganglion was the least (30.9). Extensive distribution of ENK neurons in cranial parasympathetic ganglions suggested that ENK was involved in the modulation of the splanchnomotion of the head and the face.