| 热毒宁注射液的GC/MS指纹图谱 |
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| 引用本文： | 萧伟,凌娅,毕宇安,王振中,章晨峰.热毒宁注射液的GC/MS指纹图谱[J].中国天然药物,2007,5(2):127-129. |
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| 作者姓名： | 萧伟 凌娅 毕宇安 王振中 章晨峰 |
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| 作者单位： | 江苏康缘药业股份有限公司,连云港,222001 |
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| 摘 要： | 目的:建立热毒宁注射液GC指纹图谱,比较注射液与药材之间指纹图谱的相关性,为该中药注射剂生产工艺过程及成品质量控制提供有效的方法。方法:毛细管气相色谱法,采用氢火焰检测器及质谱进行检测分析。结果:测定热毒宁注射液挥发性成分,标出其中8个共有峰,说明了其药材归属,并采用GC/MS对主要色谱峰进行了初步定性。结论:建立了GC法测定热毒宁注射液挥发性成分指纹图谱的方法,该方法准确、重现性好,为热毒宁注射液挥发性成分的质量控制提供了依据。
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| 关 键 词： | 热毒宁注射液 气相指纹图谱 |
| 文章编号： | 1672-3651（2007）02-0127-03 |
| 修稿时间： | 2006-05-25 |
GC/MS Fingerprint of Reduning Injection |
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| XIAO Wei,LING Ya,BI Yu-An,WANG Zhen-Zhong,ZHANG Chen-Feng.GC/MS Fingerprint of Reduning Injection[J].Chinese JOurnal of Natural Medicines,2007,5(2):127-129. |
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| Authors: | XIAO Wei LING Ya BI Yu-An WANG Zhen-Zhong ZHANG Chen-Feng |
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| Institution: | Jiangsu Kanion Pharmaceutical Co. ,Ltd, Lianyungang 222001, China |
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| Abstract: | AIM:To establish GC fingerprint of Reduning injection and compare the correlations of fingerprints between Reduning injections and raw materials.METHODS:Reduning injections and raw materials were analyzed by GC.The ingredients of common peaks were designated by MS.RESULTS:The volatile ingredients of Reduning injection have been determined and 8 common peaks on the fingerprints were detected.CONCLUSION:The established GC fingerprint method is accurate and reliable,which could be used for the quality control of volatile ingredients in Reduning Injection. |
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| Keywords: | GC/MS |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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