人前列腺癌组织中解脲支原体的检测

目的：检测人前列腺癌组织中解脲支原体感染的情况，探讨解脲支原体感染与前列腺癌发生的关系。方法：应用解脲支原体PCR检测试剂盒对115例不同前列腺组织标本中解脲支原体感染情况进行检测，其中前列腺癌50例，癌旁正常组织30例，良性前列腺增生组织35例。结果：前列腺癌组织、癌旁正常组织，良性前列腺增生组织中解脲支原体的感染率分别为46％、16．7％和8．6％，三者之间差异有统计学意义。前列腺癌组织的解脲支原体感染阳性率明显高于其他各组。癌旁正常组织，良性前列腺增生组织中解脲支原体感染阳性率的差异无统计学意义。结论：前列腺癌组织中解脲支原体感染率较高，解脲支原体感染与前列腺癌的发生存在一定关系。

Detection of Ureaplasma urealyticum in human prostatic carcinoma

Objective：To detect the Ureaplasma urealyticum infection in human prostatic carcinoma and explore the relationship between carcinogenesis of prostatic carcinoma and Ureaplasma urealyticum infection. Methods： Ure- aplasma urealyticum PCR diagnostic kit was employed to detect Ureaplasma urealyticum infection in 115 specimens of different prostatic lesions,including 50 prostatic carcinoma specimens,30 normal prostatic tissues adjacent to cancer tissue,35 benign prostate hyperplasia specimens. Results ： The positive rates of Ureaplasma urealyticum infection in prostatic carcinoma, normal prostatic tissue adjacent to cancer tissue and benign prostate hyperplasia were 46%, 16.7%, 8.6%, respectively, the rates of Ureaplasma urealyticum infection were significantly different. The rate of Ureaplasma urealyticum infection in prostatic carcinoma was significantly higher than that of other specimens. The difference of Ureaplasma urealyticum infection between normal prostatic tissues adjacent to cancer tissues and benign prostate hyperplasia was not significant. Conclusion： Prostatic carcinoma has a high infection rate of Ureaplasma urea- lyticum,which may be related with the carcinogenesis of prostatic carcinoma.