The impact of lifestyle behaviours,physical activity and smoking on morbidity and mortality in patients with rheumatoid arthritis |
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| Affiliation: | 1. Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK;2. NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, UK;1. Versus Arthritis Primary Care Centre, School of Primary, Community and Social Care, Keele University, Keele, Staffordshire, ST5 5BG, United Kingdom;2. MRC Versus Arthritis Centre for Musculoskeletal Health and Work, University of Southampton, UK;3. Unit of Occupational Therapy, Department of Health, Medicine and Caring Sciences, Faculty of Health Sciences, Linköping University, Department of Rheumatology, Heart and Medicine Center, Region Östergötland, Sweden;4. The British Standards Institution, Environmental Health and Safety Services and Solutions, Hillsboro, OR, USA;5. Graduate Program in Ergonomics and Biomechanics, School of Medicine, New York University, New York, NY, USA;6. Dept. of Quantitative Health Sciences, Univ of Massachusetts Medical School, Worcester, MA, USA;1. Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark;2. Department of Clinical Medicine, Aarhus University, Aarhus, Denmark;3. Danish Hospital for Rheumatic Diseases, University Hospital of Southern Jutland, Sønderborg, Denmark;4. Department of Regional Health Research, University of Southern Denmark, Odense, Denmark;5. Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Rheumatology, Lund, Sweden;6. Hospital of Southern Jutland, University Hospital of Southern Denmark, Aabenraa, Denmark;1. Academic Rheumatology, Bristol Royal Infirmary, Bristol, UK;2. Department of Nursing and Midwifery, University of the West of England, Bristol, UK;3. Department of Allied Health Professionals, University of the West of England, Bristol, UK;4. Department of Social Work, Education and Community Wellbeing, Northumbria University, Newcastle, UK;5. Department of Regional Health Research, University of Southern Denmark, Odense, Denmark;1. Department of Physical Education, Universidade Federal Rural de Pernambuco (UFRPE), Recife, Pernambuco, Brazil;2. Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil;3. Postgraduate Program in Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil;4. Hospital Israelita Albert Einstein, São Paulo, Brazil;5. University of São Paulo, Faculty of Medicine, São Paulo, Brazil;1. Department of General Practice, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands;2. Department of Orthopedics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands |
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| Abstract: | Rheumatoid arthritis (RA) is associated with pain, disability and increased risk of developing comorbidities and premature mortality. While these poor outcomes have improved in line with advances in the treatment of RA, they still persist to some degree today. Physical activity and smoking are two areas of patients’ lives where changes may have a substantial impact on the poor outcomes associated with RA. Physical activity in RA has been well studied, with many randomised trials indicating the benefits of physical activity on pain and disability. A number of observational studies have assessed the impact of smoking on RA, also indicating the benefits of quitting smoking on RA-related outcomes, but with less consistent findings, potentially due to epidemiological challenges (e.g. collider bias, recall bias). There are also a number of barriers preventing patients making these positive lifestyle changes, such as lack of time and motivation, lack of knowledge and advice, as well as disease-specific barriers, such as pain and fatigue. |
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| Keywords: | Rheumatoid arthritis Lifestyle Exercise Physical activity Smoking Barriers Facilitators |
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