Tranexamic acid in patients with intracerebral haemorrhage (STOP-AUST): a multicentre,randomised, placebo-controlled,phase 2 trial |
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| Institution: | 1. The Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia;2. Departments of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia;3. Department of Mathematics and Statistics, University of Melbourne, Melbourne, VIC, Australia;4. Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia;5. Department of Neurology, Helsinki University Hospital, Helsinki, Finland;6. Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia;7. New Zealand Brain Research Institute, Christchurch, New Zealand;8. Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan;9. Department of Neurology, Royal Adelaide Hospital, Adelaide, SA, Australia;10. Department of Neurology, John Hunter Hospital, University of Newcastle, Newcastle, NSW, Australia;11. Department of Neurology, Austin Hospital, Heidelberg, VIC, Australia;12. Department of Neurology, Western Hospital, Melbourne, VIC, Australia;13. Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan;14. Department of Neurology, China Medical University Hospital, Taichung, Taiwan;15. Department of Neurology, Princess Alexandra Hospital, Woolloongabba, QLD, Australia;p. Department of Neurology, Alfred Hospital, Monash University, Melbourne, VIC, Australia;q. Department of Clinical Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia;r. Department of Neurology, Monash Medical Centre, Monash University, Melbourne, VIC, Australia;s. School of Clinical Sciences, Monash University, Melbourne, VIC, Australia;t. Department of Neurosciences, Eastern Health Medical School, Monash University, Melbourne, VIC, Australia;u. Ambulance Victoria, Melbourne, VIC, Australia;v. Department of Neurology, Lyell McEwin Hospital, Adelaide, SA, Australia;w. Department of Radiology, Neuroradiology Section, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada;x. South Australian Health and Medical Research Institute, The University of Adelaide, Adelaide, SA, Australia;y. Sydney Partnership for Health, Education, Research and Enterprise (SPHERE), Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia;1. Department of Diagnostic Imaging, Foothills Medical Center, University of Calgary, Calgary, AB T2N2T9, Canada;2. Department of Clinical Neurosciences, Foothills Medical Center, University of Calgary, Calgary, AB T2N2T9, Canada;3. Department of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland;1. Department of Cardiovascular Sciences, University of Leicester, Leicester, UK;2. NIHR Biomedical Research Unit in Cardiovascular Disease, University of Leicester, Leicester, UK;3. The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia;4. Royal Prince Alfred Hospital, Sydney, NSW, Australia;5. The Shanghai Institute of Hypertension, Rui Jin Hospital, Shanghai Jiaotong University, Shanghai, China;6. Servicio de Neurología, Departamento de Medicina, Clínica Alemana, Universidad del Desarrollo, Santiago, Chile;7. Universidad de Chile, Santiago, Chile;8. Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, VIC, Australia;9. University of Melbourne, Melbourne, VIC, Australia;10. INSERM, U897, Bordeaux, France;11. University of Bordeaux, Bordeaux, France;12. Department of Neurology, Peking University First Hospital, Beijing, China;13. Department of Neurology, APHP – Hôpital Lariboisière, Paris, France;14. DHU NeuroVasc Paris – Sorbonne, Paris, France;15. Université Paris Diderot - Sorbonne Paris Cité, Paris, France;p. Stroke Prevention Research Unit, University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK;1. Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany;2. Hospices Civils de Lyon, Service de Biostatistique, Lyon, France;3. Université Lyon 1, Villeurbanne, France;4. Laboratoire de Biométrie et Biologie Evolutive, Equipe Biostatistique-Santé, Villeurbanne, France;5. Department of Medicine, School of Clinical Sciences, Monash University, Melbourne, VIC, Australia;6. Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan;7. Department of Data Science, National Cerebral and Cardiovascular Center, Suita, Japan;8. Center for Advancing Clinical and Translational Sciences, National Cerebral and Cardiovascular Center, Suita, Japan;9. Department of Neurology, University of Heidelberg, Heidelberg, Germany;10. Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany;11. Department of Neurology, Massachusetts General Hospital, Boston, MA, USA;12. Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA;13. Department of Neurosciences, Eastern Health and Eastern Health Clinical School, Monash University, Box Hill, VIC, Australia;14. Departments of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC, Australia;15. Centrum für Schlaganfallforschung Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany;p. Klinik und Hochschulambulanz für Neurologie, Charité-Universitätsmedizin Berlin, Berlin, Germany;q. Klinik für Neurologie Medical Park Berlin Humboldtmühle, Berlin, Germany;r. German Centre of Cardiovascular Research, Berlin, Germany;s. German Center of Neurodegenerative Diseases, Berlin, Germany;t. Department of Neurology, Royal Adelaide Hospital, Adelaide, SA, Australia;u. Acute Cerebrovascular Diagnostics Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA;v. Department of Neurosciences, Experimental Neurology, KU Leuven, University of Leuven, Leuven, Belgium;w. VIB Center for Brain and Disease Research Leuven, Belgium;x. Department of Neurology, University Hospitals Leuven, Leuven, Belgium;y. The Department of Neurology, Priority Research Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle, Newcastle, NSW, Australia;z. Université de Lille, Inserm U1171, Lille, France;11. Stroke Unit, Department of Neurology, Hospital Universitari Vall d''Hebron, Barcelona, Spain;12. Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK;13. Department of Stroke Medicine, Université Claude Bernard Lyon 1, CarMeN Laboratory, INSERM U1060/INRA 1397, Lyon, France;14. Department of Radiology, Institut de Diagnòstic per la Imatge, Hospital Dr Josep Trueta, Institut d''Investigació Biomèdica de Girona, Girona, Spain;15. Universitätsklinik für Neurologie, Mühlenkreiskliniken, Johannes Wesling Klinikum Minden, Universitätsklinikum der Ruhr-Universität Bochum, Minden, Germany;16. Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany;17. Department of Neurology, Aarhus University Hospital, Aarhus, Denmark;18. Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA;19. Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia;110. Department of Neurology, Austin Health, Heidelberg, VIC, Australia;111. Department of Human Neurosciences, University of Rome “La Sapienza”, Rome, Italy;112. Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan;113. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden;114. Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia;115. Dell Medical School, University of Texas at Austin, Austin, TX, USA;1. Department of Medicine and Neurology, Melbourne Brain Centre, University of Melbourne, Melbourne, VIC, Australia;2. Department of Radiology, University of Melbourne, Melbourne, VIC, Australia;3. Royal Melbourne Hospital, and Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia;4. Department of Medicine, School of Clinical Science, Monash University, Melbourne, VIC, Australia;5. Department of Neurosciences, Eastern Health and Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia;6. Department of Neurology, Ruprecht Karls University Heidelberg, Heidelberg, Germany;7. Department of Neuroradiology, Ruprecht Karls University Heidelberg, Heidelberg, Germany;8. Department of Medicine, University of Melbourne, Melbourne, VIC, Australia;9. Department of Neurology, University of Melbourne, Melbourne, VIC, Australia;10. Austin Health, and Department of Medicine, Western Hospital, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia;11. Department of Neurology, Priority Research Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle, Newcastle, NSW, Australia;12. Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan;13. Department of Neurology, Royal Adelaide Hospital, Adelaide, SA, Australia;14. Department of Neurology, Faculty of Medicine Mannheim, University of Heidelberg, Mannheim, Germany;15. Department of Neurology, Hospital CHU Lille, Lille, France;p. Department of Neurology, Hospital Vall d''Hebron, University of Barcelona, Barcelona, Spain;q. Department of Neurology, Western Health, Sunshine Hospital, Melbourne, VIC, Australia;r. Department of Neurology, Helsinki University Hospital, Helsinki, Finland;s. Department of Neurology, Auckland City Hospital, University of Auckland, Auckland, New Zealand;t. Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia;u. Division of Neurology, University of Alberta, Edmonton, AB, Canada;v. Department of Neurology, Singapore General Hospital, National Neuroscience Institute, Singapore;w. Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany;x. Department of Neurology and Neurogeriatry, Johannes Wesling Medical Centre Minden, University Hospital of Ruhr-University Bochum, Bochum, Germany;y. Department of Neurology, Girona University Hospital, Biomedical Research Institute of Girona, Girona, Spain;z. Department of Neurology, Sapienza University of Roma, Rome, Italy |
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