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Genetic underpinnings of asthenozoospermia
Institution:1. Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China;2. Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China;3. College of Life Science, Hunan Normal University, Changsha, China;1. Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai 200011, China;2. Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China;3. State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211116, China;4. Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China;5. Anhui Province Key Laboratory of Reproductive Health and Genetics, Anhui Medical University, Hefei 230022, China;6. Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei 230022, China;7. State Key Laboratory of Reproductive Medicine, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215002, China;8. Suzhou Municipal Hospital, Suzhou 215002, China;9. Polyclinique les Jasmins, Centre d’Aide Médicale à la Procréation, Centre Urbain Nord, 1003 Tunis, Tunisia;10. Genetic Epigenetic and Therapies of Infertility, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique UMR 5309, Université Grenoble Alpes, Grenoble 38000, France;11. Centre Hospitalier Universitaire de Grenoble, UM GI-DPI, Grenoble 38000, France;12. Centre Hospitalier Universitaire de Grenoble, UM de Génétique Chromosomique, Grenoble 38000, France;13. Department of Gynecology and Obstetrics, the Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China;1. College of Animal Science and Technology, Northwest A&F University, Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, Shaanxi 712100, PR China;2. Shaanxi Provincial Engineering and Technology Research Center of Cashmere Goats, Yulin University, Yulin, Shaanxi 719000, PR China;3. Life Science Research Center, Yulin University, Yulin, Shaanxi 719000, PR China;4. Shaanxi Province “Four Subjects One Union” Sheep and Goat Engineering & Technology University & Enterprise Alliance Research Center, Yulin, Shaanxi 719000, PR China
Abstract:
Keywords:male infertility  asthenozoospermia  sperm motility  genetic defects  intracytoplasmic sperm injection
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