Intravenous self-administration of morphine by naive mice |
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| Authors: | Hugh E Criswell Annette Ridings |
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| Institution: | Department of Psychology, East Tennessee State University, Johnson City, TN 37614, USA |
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| Abstract: | A simple method for IV self-administration of drugs by mice is described. When morphine (0.5 mg/kg) was made contingent on a nosepoke response, naive mice increased their rate of nosepoking when compared either with animals receiving contingent saline vehicle injectionsor yoked control animals receiving noncontingent morphine. |
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| Keywords: | Morphine Opiate Self-administration Nosepoke Mouse |
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