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The influence of intestinal lymphatic transport on the systemic exposure and brain deposition of a novel highly lipophilic compound with structural similarity to cholesterol
Authors:Suzanne M. Caliph  Fried W. Faassen  Christopher J. H. Porter
Affiliation:1. Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville campus), , Parkville, Vic, Australia;2. Pharmaceutical Sciences and Clinical Supply, Merck Sharp & Dohme, , Oss, The Netherlands
Abstract:
Keywords:brain deposition  drug absorption  lipid‐based formulation  lymphatic transport  poorly water‐soluble drugs
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