Affiliation: | 1. Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael's Hospital, , Toronto, Ontario, Canada;2. Division of Endocrinology and Metabolism, University of Toronto, , Toronto, Ontario, Canada;3. Pennington Biomedical Research Center, Louisiana State University System, , Baton Rouge, Louisiana;4. Research and Development, AstraZeneca, , Wilmington, Delaware;5. Research and Development, AstraZeneca, , M?lndal, Sweden |