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| 儿童和青少年甲状腺功能亢进症的131I治疗 | |
| 引用本文： | 赵德善,孔繁振,司宏伟,朱亦堃. 儿童和青少年甲状腺功能亢进症的131I治疗[J]. 中华内分泌代谢杂志, 2006, 22(6): 566-568 |
| 作者姓名： | 赵德善 孔繁振 司宏伟 朱亦堃 |
| 作者单位： | 1. 030001,太原,山西医科大学第一医院核医学科 2. 北京,军区解放军总医院核医学科 3. 北京,中国医学科学院肿瘤医院核医学科 4. 山西医科大学第二医院内分泌科 |
| 摘 要： | 对适宜^131Ⅰ治疗的儿童和青少年甲亢患者进行治疗前后的疗效观察研究。临床确诊及对抗甲亢药物耐药或有禁忌证的31例患者接受了^131Ⅰ治疗。其中15例痊愈，11例明显好转，5例甲减；18例突眼患者中，8例突眼基本恢复正常，4例缓解，5例无变化和1例加重。对不宜行抗甲亢药物治疗的10岁以上甲亢患者来说，^131Ⅰ是一种相对安全、有效的治疗方法。 |
| 关 键 词： | 甲状腺功能亢进症 碘放射性同位素 治疗 随访研究 儿童和青少年 |
| 收稿时间： | 2005-10-17 |
| 修稿时间： | 2005-10-17 |
131I treatment of hyperthyroidism in children and adolescents |
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| ZHAO De-shan,KONG Fan-zhen,SI Hong-wei,ZHU Yi-kun. 131I treatment of hyperthyroidism in children and adolescents[J]. Chinese Journal of Endocrinology and Metabolism, 2006, 22(6): 566-568 | |
| Authors: | ZHAO De-shan KONG Fan-zhen SI Hong-wei ZHU Yi-kun |
| Affiliation: | Department of Nuclear Medicine, The First Hospital, Shanxi Medical University, Taiyuan 030001 |
| Abstract: | The efficacy of ~(131)I treatment of hyperthyroidism in children and adolescents was evaluated. Being unsuitable for medical therapy,31 patients (aged 11-18 years) with hyperthyroidism received ~(131)I treatment with a dose of 0.925-3.33 MBq/g of thyroid and were followed-up for 20 to 76 months.Fifteen patients were euthyroid,5 suffered from late-onset hypothyroidism,and 11 were still hyperthyroid,but their symptoms and signs of hyperthyroidism were markedly improved.Of the 18 patients with thyroid-associated ophthalmopathy (TAO),8 patients recovered,4 were improved,TAO in 1 patients deteriorated and in S patients remained unchanged.~(131)I is a relative safe and effective treatment for children and adolescents above 10 years old with hyperthyroidism,being unsuitable for medical therapy. |
| Keywords: | Hyperthyroidism Iodine radioisotopes Treatment Follow-up studies Children andadolescents |
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