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双波长分光光度法测定复方地氯霜中氯霉素的含量
引用本文:卢今,柳涌. 双波长分光光度法测定复方地氯霜中氯霉素的含量[J]. 安徽医药, 2007, 11(12): 1084-1085
作者姓名:卢今  柳涌
作者单位:安徽省立医院药剂科,安徽,合肥,230001;安徽省立医院药剂科,安徽,合肥,230001
摘    要:目的建立复方地氯霜中氯霉素的含量测定方法。方法采用双波长分光光度法测定氯霉素的含量。选择测定波长为268 nm,参比波长为248 nm。结果氯霉素的平均回收率为104.3%,RSD为2.93%(n=6)。结论该方法简便、准确,适用于该制剂的质量控制。

关 键 词:双波长分光光度法  氯霉素
收稿时间:2007-08-22
修稿时间:2007-08-22

Determination of chloramphenicol in dexamethasone and chloramphenicol compound cream by dual-wavelength spectrophotometry
LU Jin,LIU Yong. Determination of chloramphenicol in dexamethasone and chloramphenicol compound cream by dual-wavelength spectrophotometry[J]. Anhui Medical and Pharmaceutical Journal, 2007, 11(12): 1084-1085
Authors:LU Jin  LIU Yong
Abstract:Aim To establish a method for the determination of chloramphenicol in dexamethasone and chloramphenicol compound cream.Methods A dual-wavelength spectrophotometry was used.The selected determining wavelength was 268 nm and the reference wavelength was 248 nm.Results The average recovery of chloramphenicol was 104.3%,and RSD was 2.93%(n=6).Conclusion This method is simple,accurate and suitable for assay of the preparation.
Keywords:dual-wavelength spectrophotometry  chloramphenicol
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