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结直肠癌微血管密度与其病理特征的关系
引用本文:牛保华,吴萍,赵卫. 结直肠癌微血管密度与其病理特征的关系[J]. 山西医科大学学报, 2007, 38(2): 124-125
作者姓名:牛保华  吴萍  赵卫
作者单位:1. 河南大学医学院神经生物学研究所,开封,475004;河南大学医学院病理学教研室,开封,475004
2. 河南大学医学院神经生物学研究所,开封,475004
3. 开封市第一人民医院
基金项目:河南省教育厅自然科学基金
摘    要:目的探讨结直肠癌组织中微血管密度与结直肠癌临床病理特征之间的关系。方法应用抗CD105抗体检测结直肠癌组织中微血管密度(MVD)。结果不同分化程度结直肠癌MVD比较差异有统计学意义(P〈0.05);不同浸润深度结直肠癌MVD比较差异有统计学意义(P〈0.05);有淋巴结转移组MVD与无淋巴结转移组比较差异有统计学意义(P〈0.05)。结论MVD与结直肠癌的分化程度、浸润深度及淋巴结转移有关。

关 键 词:结直肠肿瘤  微血管密度  免疫组织化学
文章编号:1007-6611(2007)02-0124-02
修稿时间:2006-10-26

Relationship between MVD and clinical pathologic features in tissues of colorectal carcinoma
NIU Bao-hua,WU Ping,ZHAO Wei. Relationship between MVD and clinical pathologic features in tissues of colorectal carcinoma[J]. Journal of Shanxi Medical University, 2007, 38(2): 124-125
Authors:NIU Bao-hua  WU Ping  ZHAO Wei
Abstract:Objective To study the relationship between microvessel density(MVD)and clinical pathologic features in tissues of colorectal carcinoma.Methods MVD in colorectal carcinoma was examined by immunohistochemical S-P method with anti-CD105 antibody.Results MVD was significantly different in different pathological grading(P<0.05),different invasive depth(P<0.05),and also significantly different between with and without lymph node metastasis(P<0.05).Conclusion MVD was significantly correlated with histology grade,invasion depth and lymph node metastasis of colorectal carcinoma.
Keywords:colorectal neoplasms  microvessel density  immunohistochemistry
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