| 益智灵对小鼠学习记忆的促进作用 |
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| 引用本文： | 顾长虹 陈湖海. 益智灵对小鼠学习记忆的促进作用[J]. 中成药, 1995, 17(11): 27-28 |
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| 作者姓名： | 顾长虹 陈湖海 |
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| 作者单位： | 上海第二军医大学 |
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| 摘 要： | 采用一次性训练的被动回避反应—“Ｙ”电迷宫法，观察益智灵对亚硝酸钠和３０％乙醇致小鼠记忆障碍的改善作用，并与尼莫地平和神经生长因子的作用作了比较。３种药物对改善亚硝酸钠致记忆巩固障碍均有效。益智灵和神经生长因子还拮抗３０％乙醇致记忆再现障碍。另结果表明益智灵对正常小鼠学习行为有促进作用，其它两药未见有此作用。
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| 关 键 词： | 益智灵，尼莫地平，神经生长因子，记忆障碍，学习，“Y”电迷宫法 |
Promoting Action of Yizhiling Oral Liquid (Radix Polygalae,Radix Astragail seu Hedysari,etc.)on learning Memory of Mice |
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| Gu Changhong, Chen Huhai,et al.. Promoting Action of Yizhiling Oral Liquid (Radix Polygalae,Radix Astragail seu Hedysari,etc.)on learning Memory of Mice[J]. Chinese Traditional Patent Medicine, 1995, 17(11): 27-28 |
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| Authors: | Gu Changhong Chen Huhai et al. |
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| Abstract: | The improving actions of Yizhiling Oral Liquid on memory disorder of mice induced by sodium nitrite or 30%alcohol were investigated by"Y"electric labyrinthian method-one time training passive avoidance reaction. Also its action was compared with that of nimodipine and NGF. Three drugs all have the curative effect on memory-strengthening disorder induced by sodium nitrite.Yizhiling Oral Liquid and NGF have antagonism on memory reappearance disorder induced by 30%alcohol.Another result indicated that Yizhiling Oral Liquid has promoting action on learning function of normal mice,the other two have no this ac tion. |
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| Keywords: | Yizhiling Oral Liquid,nimodipine.NGF.menory disorder," Y" electric labyrinthian method |
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