血管内皮生长因子及血管内皮生长因子受体在急性肺损伤中作用的研究

血管内皮生长因子是作用于血管内皮细胞的重要血管调节因子,它通过与内皮上的特异受体结合,可发挥促进内皮细胞增殖、分化、诱导血管生成、增加微血管通透性等多种功能.近年研究显示血管内皮生长因子在不同原因、不同阶段急性肺损伤中所起的作用不同.

Study on role of vascular endothelial growth factor and vascular endothelial growth factor receptor in acute lung injury

Vascular endothelial growth factor is important vascular endothelial adjusting factor. It can promote proliferation and differentiation of endothelial cells,induce angiogenesis, and increase capillary permeability through binding to its specific receptor. Recent researches have shown that vascular endothelial growth factor plays different roles in acute lung injury with different reasons in different stages.