青岛沿海地区肠易激综合征患者临床特征的评估

背景:肠易激综合征(IBS)是一种常见的功能性肠病,但目前我国沿海地区IBS的研究相对较少。目的:评价青岛沿海地区IBS患者的临床特征,以探讨其病因。方法:纳入2007年1～12月诊断符合罗马Ⅲ标准的青岛大学医学院附属医院消化科门诊IBS患者,以问卷形式调查患者的一般资料、临床症状、饮食习惯等情况,分析相关危险因素。结果:共纳入IBS患者6360例,占总体门诊患者的19.6%。IBS患者男女之比为1:1.12,以中青年、教育水平较高者、低收入人群和城市居民为主,多数患者生活环境一般,春季是发病高峰。IBS亚型以腹泻型(IBS-D)最常见(49.3%),且最易出现肠道症状。与正常对照组相比,IBS患者的饮食习惯具有一定倾向性,更易发生上消化道和全身症状。结论:青岛沿海地区IBS发生率不低,以女性患者和IBS-D亚型多见,并受环境和饮食等多种因素的影响。

Evaluation of Clinical Characteristics of Irritable Bowel Syndrome in Coastal Areas of Qingdao

Background： Irritable bowel syndrome （IBS） is a common functional intestinal disorder, however, it is relatively less frequently studied in the coastal areas of China. Ahns： To investigate the clinical characteristics of IBS patients in the coastal areas of Qingdao and to appraise the causes of IBS. Methods： From January to December 2007, IBS outpatients coincident with Rome III criteria at the GI clinics of the Affiliated Hospital of Medical College, Qingdao University were enrolled in this study. The general data, clinical manifestations and dietary habits of the participants were inquired by questionnaires, and the relevant risk factors were analyzed. Results： A total of 6360 outpatients were diagnosed as IBS based on Rome IU criteria, occupying 19.6% of the overall patients attending our GI clinics. The ratio of male to female was 1：1.12. Most IBS patients were young and urban dwellers, with high education levels, low income and common living conditions. Spring was the most common season of IBS attack. Of all the IBS patients, diarrheapredominant IBS （IBS-D） was the most common subtype （49.3%）, and was more likely to have intestinal manifestations. Compared with the normal control group, IBS patients had some bias in their dietary habits, and were more likely to have upper gastrointestinal and systemic manifestations. Conclusions： Incidence rate of IBS in coastal areas of Qingdao is not low, the female patients and IBS-D subtype are more, and it may be related with environmental factors and dietary habits.