医用生物蛋白胶胃镜下封堵治疗食管瘘的临床研究

目的:探讨医用生物蛋白胶封堵治疗食管瘘的方法和效果。方法:对近5年11例碘剂造影和/或胃镜检查证实为食管-呼吸道瘘和食管-颈部瘘的患者,应用医用生物蛋白胶经胃镜进行封堵瘘口治疗。结果:11例患者胃镜下应用医用生物蛋白胶封堵瘘口均获成功,其中9例经1次封堵后窦道完全愈合,2例经2次封堵后窦道完全愈合。平均住院时间为27d,平均费用为2.45万元。随访3～6个月无复发,无不良并发症。结论:与常规保守治疗比较,胃镜下医用生物蛋白胶封堵食管瘘口,可减少住院时间,降低住院费用。

Occlusion of Esophageal Fistula with Medicinal Albumin Gel under Gastroscope

OBJECTIVE:To explore the method and efficacy of occlusion with medicinal albumin gel for esophageal fistula. METHODS:Over the recent 5 years,a total of 11 patients with esophagus -respiratory fistula or esophagus-neck fistula confirmed by iodine imaging and / or gastroscopy were occluded with medicinal albumin gel under endoscope. RESULTS:The occlusion with medicinal albumin gel for esophageal fistula was successful in all the 11 cases,and 9 out of 11 were completely healed after one time occlusion treatment and the other 2 cases were completely healed after the second occlusion treatment. The average hospital stay was 27 days and the average cost was 24,500 yuan. There was no recurrence after follow-up of 3 to 6 months,nor was there any adverse complication. CONCLUSION:Compared to the conventional conservative treatment,occlusion with medicinal albumin gel for esophageal fistula under endoscope can reduce the length of hospital stay and the cost of hospitalization.