Langerhans cell histiocytosis involving the corpus callosum and cerebellum: gadolinium-enhanced MRI |
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Authors: | J. M. Strottmann L. E. Ginsberg C. Stanton |
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Affiliation: | (1) Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Medical Center Boulevard, 27157-1088 Winston-Salem, NC, USA;(2) Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC, USA;(3) Present address: Diagnostic Radiology, Medical Center, Room HX-304, 800 Rose Street, 40536-0084 Lexington, KY, USA;(4) Present address: Department of Radiology, University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030 Houston, TX, USA |
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Abstract: | Langerhans cell histiocytosis is a systemic disorder consisting of abnormal histiocyte proliferation, in the form of focal deposits. Central nervous system involvement is most common in the hypothalamus, although other sites have been described, such as the cerebellum and the meninges. We present a case with presumed involvement of the corpus callosum and cerebellum, demonstrating gadolinium enhancement on MRI. |
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Keywords: | Histiocytosis Langerhans cell Brain diseases Magnetic resonance imaging |
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