124例药品不良反应报告分析

目的分析引起不良反应的药物临床表现，促进合理用药。方法对124例药品不良反应（ADR）报告进行分析。结果124例ADR报告涉及药物42种，其中抗感染药物引起的不良反应发生率居首位，占70．42％，静脉给药产生ADR最多占73．24％，女性患者多于男性患者。不良反应的分类以皮肤及其附件损害最多，其次分别为神经系统和消化系统反应。结论ADR的发生与患者因素、药物因素及给药途径有关。应加强ADR蓝测工作，确保安全、有效、合理用药。

Analysis of Adverse Reactions in 124 Cases

OBJECTIVE To analyze the clinical manifestations of drug-induced adverse reactions for rational drug use.METHODS 124 cases reports of Adverse Drug Reaction (ADR) were analyzed.RESULTS 124 ADR case reports were associated with 42 drugs.The rate of the advarse reactions caused by anti-infective drugs ranks first-70.42%.The ADR given via intravenous route were maximum-73.24%,the female patients are more than the male.Most of ADR were found in the skin and its appendages,nervous systen and digestive system.CONCLUSION The occurrence of adverse reactions to drugs was related to patients,drugs and route of administration.We should intensify monitoring of ADR in order to ensure the safety,effectiveness and rationality of drug usage.