中药复方崩大碗汤改良保留灌肠法治疗慢性肾功能衰竭的临床研究

目的:为验证中药复方崩大碗汤在治疗慢性肾功能衰竭(CRF)中的作用,采用不同灌肠方式对CRF患者进行治疗。方法:收集年龄20～70岁的CRF患者150例,随机分为观察组(100例)及对照组(50例)。两组均在基础治疗基础上加复方崩大碗汤保留灌肠,对照组采用传统的一次性灌肠袋灌肠,观察组采用本院一次性吸痰管灌肠。观察患者依从性、生化及综合疗效指标,并进行数据分析。结果:观察组与对照组相比,依从性、治疗后生化指标改变、总疗效均有显著性差异(P<0.05)。结论:中药复方崩大碗汤治疗CRF作用明显,采用改良的灌肠方法效果更好,患者更能接受。

Clinical Study of Multiple Centella Decoction lmproved Enema in Treating Chronic Renal Failure

Objective:To validate the clinical effect of Multiple centella decoction-enema in the course of treating CRF,we adopted different clysters and gave considerate care.Methods:We collected 150 cases of CRF aged at 20 ～70 years randomly divided into observe group(100 cases) and control group(50 cases).Two groups were treated by the same routine and Multiple centella decoction-enema,but the control with traditional enema and the observe with improved enema.The examined targets were compliance,integrated efficacy evaluation,biochemistry parameters’ diversifications before and after treatment such as serum creatinine(SCr)、serum urea nitrogen(BUN) and clinical symptom score of TCM,the dates were treated by statistics.Results:The observe group’s compliance,integrated efficacy,biochemistry parameters’ diversification after treatment were significantly better than control group(P <0.05).Conclusion:The Multiple centella decoction-enema has distinct effect in treating CRF,and the improved enema is better than the traditional one.