| 乙醇脂质体透皮作用的研究与发展 |
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| 引用本文： | 王建,钟延强.乙醇脂质体透皮作用的研究与发展[J].药学实践杂志,2003,21(5):275-277. |
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| 作者姓名： | 王建 钟延强 |
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| 作者单位： | 第二军医大学药学院,上海,200433 |
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| 摘 要： | 目的：介绍乙醇脂质体透皮作用的研究与发展。方法：综合分析乙醇脂质体的组成及一般特性、制备及乙醇脂质体载药系统透皮给药的药剂学促透机制、最新的基础实验和研究进展。结果：作为各种药物的载体，乙醇脂质体具有其良好的药物包裹率和显著的促进药物透皮吸收特性。结论：乙醇脂质体新剂型透皮给药具有广阔的应用前景。
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| 关 键 词： | 乙醇脂质体 透皮作用 研究发展 药剂学 促透机制 |
| 文章编号： | 1006-0111(2003)05-0275-03 |
| 收稿时间： | 4/7/2003 12:00:00 AM |
| 修稿时间： | 2003年4月7日 |
Study and development of ethosome as drug delivery carrier in skin penetration |
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| WANG Jian and ZHONG Yan-qiang.Study and development of ethosome as drug delivery carrier in skin penetration[J].The Journal of Pharmaceutical Practice,2003,21(5):275-277. |
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| Authors: | WANG Jian and ZHONG Yan-qiang |
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| Institution: | Department of Pharmaceutics, College of Pharmacy, Second Military Medical University, Shanghai 200433 , China;Department of Pharmaceutics, College of Pharmacy, Second Military Medical University, Shanghai 200433 , China |
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| Abstract: | OBJECTIVE: To report the research and development of the ethosome. METHODS:The analyses for the information involved with the character and components of the ethosome , and the pharmaceutics mechanism of the transdermal drug delivery system that preparated by the technology of the ethosome encapsulation , and its newly basic experiment and reseach progress. RESULTS: As a carrier of various drugs, the ethosome shows good drug encapsulation and marked acceleration of trasdermal drug delivery. CONCLUSIONS: The technology of liposome encapsulation will be appear a wider foreground in futue. |
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| Keywords: | ethosome encapsulation ratio transdermal drug delivery carrier skin penetration |
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