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引用本文: | 陈娟,陈敏英,管向东,欧阳彬,杨春华,黎丽芬,吴健锋,刘紫锰,刘勇军.������ѪҺ���������ظ�Ⱦ�ۺ������μ�ֵ�о�[J].中国实用外科杂志,2008,28(6):456-458. |
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作者姓名: | 陈娟 陈敏英 管向东 欧阳彬 杨春华 黎丽芬 吴健锋 刘紫锰 刘勇军 |
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作者单位: | ??????????????????????????????????r510080 |
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摘 要: | 目的 探讨连续性血液净化(CBP)治疗普通外科严重感染综合征的临床价值.方法 回顾性分析中山大学附属第一医院SICU在2006-01-01-2007-12-31期间52例接受CBP治疗的严重感染综合征(severe sepsis)病人资料.结果 CBP治疗时间(13.5±29.4)d,在CBP治疗期间分别采用低分子质量肝素抗凝11例(21.2%)、体外肝素抗凝13例(25.0%)、无抗凝19例(36.5%),未发生严重出血并发症.52例病人好转16例(30.8%),自动放弃治疗19例(36.5%),ICU内死亡17例(32.7%).抗凝方式、手术类型、感染部位等对CBP疗效影响差异无统计学意义.结论 CBP是外科严重感染综合征病人重要治疗措施之一,治疗过程中应采取个体化抗凝方案.
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关 键 词: | 连续性血液净化 严重感染综合征 抗凝 连续性 血液净化 严重 感染综合征 救治 价值研究 patients sepsis severe surgical treatment purification blood 方案 治疗过程 治疗措施 外科 统计学意义 差异 疗效影响 |
文章编号: | 1005-2208(2007)06-0456-03 |
修稿时间: | 2008年3月12日 |
Continuous blood purification in the treatment of surgical severe sepsis patients |
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Abstract: | ??Objective:To study the category of anticoagulant during the treatment of continuous blood purification in surgical severe sepsis patients and research the influence of the operation and infection on the effect of CBP. Methods:All severe sepsis patients who underwent CBP in the SICU of the First Affiliated Hospital of Sun Yet-sea University,from January 2006 to December 2007,were analysed retrospectively. Results:A total of 52 patients were included (42 males and 10 females) with the age of 60.8±16.0 years,and the time of CBP was 13.5±29.4 days.Eleven cases (21.15%) were anticoagulated with low molecular weight heparin,13 cases (25.00%) with heparin in vitro,19 cases (32.69%) completed the CBP without anticoagulant.The bleeding associated with anticoagulation was not observed.The impact of anticoagulation, operation and infection on the curative effect of CBP wasn't different significantly. Conclusion:CBP is a important therapy for surgical severe sepsis patients. The modality of anticoagulation should be individualization in the process of CBP. |
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