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生物碱类成分含量测定分析方法研究进展
引用本文:任海勇,冯群,黄伟,李晓骄阳.生物碱类成分含量测定分析方法研究进展[J].中国药物警戒,2012(10):622-624.
作者姓名:任海勇  冯群  黄伟  李晓骄阳
作者单位:1. 济南杏林生物技术有限公司,山东 济南 250101
2. 天津中医药大学,天津300073
3. 山东省中医药研究院,山东 济南 250014
4. 中国药科大学药学院,江苏 南京 211198
基金项目:重大新药创制专项企业创新药物孵化基地建设项目课题-治疗缺血性脑血管病的中药一类新药研制(2010ZX09401-302-2-11)
摘    要:生物碱类成分是一类重要的具有多种多样的生物活性的天然含氮有机化合物,其含量测定方法多种多样,关于其定性、定量的方法得到了广泛深入的研究.本文就近年来有关生物碱类成分含量的测定分析方法研究进展作一综述,以期为生物碱类成分含量测定方法的进一步研究提供文献依据和分析思路.

关 键 词:总生物碱  单体生物碱  含量测定

Research Development on the Analytical Method of Content Determination about Alkaloids Component
Institution:REN Hai-yong1 FENG Qun2 HUANG Wei3 LI Xiao-jiaoyang4(1Jinan Xinglin Biotechnology Co.,Ltd.,Shandong Jinan 250101,China;2Tianjin University of Traditional Chinese Medicine,Tianjin 300073,China;3Shandong Research Academy of TCM,Shandong Jinan 250014,China;4Pharmacy College of China Pharmaceutical University,Jiangsu Nanjing 211198,China)
Abstract:Alkaloids component is an important kind of natural nitrogenous organic compounds with diffenrent kinds of biological activities.The content determination methods are classified into total alkaloid and monomer alkaloid content determination.The methodology research develops fast at present.Both the advantages and disadvantages of each methodology and the advanced aspects have been made highlighting progress.In this paper,the research development on the analytical method of content determination about alkaloids component are reviewed,to provide a basis and analysis methods for the further study of the analytical method for establishing the more efficient,more sensitive,more accurate content determination method about alkaloids component.
Keywords:total alkaloids  monomer alkaloid  content determination
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