| 维生素K1注射液不良反应146例文献分析 |
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| 引用本文： | 黄元,王春婷,田月洁. 维生素K1注射液不良反应146例文献分析[J]. 中国药物警戒, 2012, 9(7): 427-430 |
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| 作者姓名： | 黄元 王春婷 田月洁 |
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| 作者单位： | 1. 山东省药品不良反应监测中心,山东济南,250013
2. 国家食品药品监督管理局药品评价中心,北京,100045 |
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| 摘 要： | 目的 探讨维生素K1注射液致不良反应的一般规律特点,为临床合理用药提供参考.方法 检索中国期刊全文数据库,对2011年12月31日之前国内公开发表文献中,有关维生素K1注射液致不良反应146例个案报道进行回顾性分析.结果 维生素K1注射液发生的不良反应可能与药物因素、患者自身因素、临床使用因素相关.结论 临床应合理使用维生素K1注射液,重视药物不良反应的临床监测,确保用药安全.
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| 关 键 词： | 维生素K1注射液 不良反应 文献分析 |
Literature Analysis of 146 Cases of Adverse Drug Reactions Induced by Vitamin-K1 Injection |
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| HUANG Yuan , WANG Chun-ting , TIAN Yue-jie. Literature Analysis of 146 Cases of Adverse Drug Reactions Induced by Vitamin-K1 Injection[J]. Chinese JOurnal of Pharmacovigilance, 2012, 9(7): 427-430 |
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| Authors: | HUANG Yuan WANG Chun-ting TIAN Yue-jie |
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| Affiliation: | 1(1Shandong Center for ADR Monitoring,Jinan 250013,China;2Center for Drug Reevaluation SFDA Beijing 100045,China) |
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| Abstract: | Objective We probe into the status,characteristics and influencing factors of ADR cases induced by vitamin-K1 injection,for providing a reference for clinical treatment.Methods Date were collected from domestic published literatures from "China Journal Full-text Database" before December 31,2011 and 146 case reports of adverse drug reactions induced by vitamin-K1 injection were analyzed retrospectively.Results Adverse drug reactions induced by vitamin-K1 injection may be related to pharmaceutical factors,patients’ factors and clinical using factors.Conclusion Vitamin-K1 injection should be used reasonably and attach importance to monitoring of clinical to ensure the safety of medication. |
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| Keywords: | vitamin-K1 injection adverse drug Reactions literature analysis |
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