肠道微生态和老龄化

肠道微生态在保持宿主健康、提供能量和营养素,抵抗生物体侵袭方面具有重要作用。研究表明,老年人肠道菌群中兼性厌氧菌数量增加,厌氧乳酸杆菌等厌氧菌和双歧杆菌等有益菌数量减少,菌群物种多样性降低。这些变化均会导致结肠内腐败代谢活动增多,使老年人对疾病的易患性增加。现对近年来老年人肠道微生态的研究以及益生菌在老年人口中的应用情况进行总结,以提高对老年人肠道微生态相关研究的重视。

Intestinal Microbiota and Aging

The intestinal microbiota is important for maintenance of host health,providing energy,nutrients and protection against invading organisms.Recent studies indicate in elderly,increased numbers of facultative anaerobes,in conjunction with a decrease in benecial organisms such as the anaerobic lactobacilli and bidobacteria,amongst other anaerobes,along with a general reduction in species diversity in most bacterial groups,which results in increased corruptive metabolic activity in colon and a greater susceptibility to disease.Here is to make a summary on the recent ndings of the intestinal microbiota and the application of probiotics in the elderly,to generate due attention to the related research.