| 雷公藤茎、叶的抗炎镇痛药理作用研究 |
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| 引用本文： | 李鸣,夏志林,叶树范.雷公藤茎、叶的抗炎镇痛药理作用研究[J].海峡药学,1999,11(3):27-28. |
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| 作者姓名： | 李鸣 夏志林 叶树范 |
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| 作者单位： | [1]福建省药品检验所 [2]福建省医学科学研究所 |
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| 摘 要： | 雷公藤叶吕提取物４００、２００ｍｇ／ｋｇｉ．ｇ给药，可明显减轻角又菜胶引起大鼠足跖肿胀和二甲苯引起小鼠耳廓的肿胀作用，对醋酸和小鼠扭体反应有明显抑制作用，表明雷公藤叶具有明显的抗炎，镇痛作用。
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| 关 键 词： | 雷公藤 抗炎 镇痛 茎 叶 水提取物 |
Study on Antiinflammatory and Analgesic Effects of Stalk and Leave of Tripterygium |
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| Li Ming, Xia Zhiling.Study on Antiinflammatory and Analgesic Effects of Stalk and Leave of Tripterygium[J].Strait Pharmaceutical Journal,1999,11(3):27-28. |
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| Authors: | Li Ming Xia Zhiling |
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| Institution: | Li Ming; Xia Zhiling(Fujian institute for drug control) (Fujain institute of medical science)Ye shufan(Fuzhou institute of medical science) |
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| Abstract: | The water extract of stalk and leave of tripterygium was studied on antiinflammatory and analgesic effects in some mouse or rat models. It (400, 200 mg/kg respectively; po.; n =10)markedly ame-liorated paw edema caused by carrageenin(P<0.001,P<0. 01 )in rats. It significantly decreased swelling of mice ear(P<0. 001,P<0.01 )by mduced dimethylbenzene and frequencies of twisting reaction induced by acetic acid(P<0.01,P<0.05)inmouse. The results that stalk and leave of tripterygium had antiinflamma-tory and anagesic actions on animals. |
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| Keywords: | Tripterygium Anti-inflammatory analgesic |
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