Long-term outcome of myeloablative allogeneic stem cell transplantation for multiple myeloma. |
| |
| Authors: | John Kuruvilla John D Shepherd Heather J Sutherland Thomas J Nevill Janet Nitta Aulan Le Donna L Forrest Donna E Hogge Julye C Lavoie Stephen H Nantel Cynthia L Toze Clayton A Smith Micheal J Barnett Kevín W Song |
| |
| Institution: | The Leukemia/Bone Marrow Transplantation Program of British Columbia, Division of Hematology, Vancouver General Hospital, British Columbia Cancer Agency and the University of British Columbia, Vancouver, British Columbia, Canada. |
| |
| Abstract: | Allogeneic stem cell transplantation (alloSCT) has been used in the hopes of harnessing the curative potential of the graft-versus-myeloma effect. This study examines the long-term outcomes of a large cohort of patients with myeloma who were treated with myeloablative alloSCT at a single center. Comparisons are made with those who were treated with autologous stem cell transplantation (ASCT). Between January 1989 and February 2002, 158 patients age10 years post myeloablative alloSCT, similarly there are long-term survivors post-ASCT. Myeloablative alloSCT should not be considered standard treatment, and should only be considered in the context of a clinical trial. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
