Focal lobular spermatogenesis and pubertal acceleration associated with ipsilateral Leydig cell hyperplasia |
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| Authors: | Leung A C Kogan S J |
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| Institution: | Department of Urology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA. |
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| Abstract: | Leydig cell tumors of the testis are the underlying cause in about 10% of the cases of precocious puberty in boys. Leydig cell hyperplasia is a less well-characterized cause, with an undocumented frequency. We describe a boy with precocious puberty associated with ipsilateral testicular enlargement and focal Leydig cell hyperplasia with spermatogenesis limited to the local adjacent testicular tissue. |
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