| 紫杉醇联合卡铂治疗晚期非小细胞肺癌 |
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| 引用本文： | 关琦,曲洪澜,陶丽艳,辛国祥.紫杉醇联合卡铂治疗晚期非小细胞肺癌[J].内蒙古医学杂志,2004,36(2):86-87. |
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| 作者姓名： | 关琦 曲洪澜 陶丽艳 辛国祥 |
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| 作者单位： | 内蒙古林业总医院肿瘤科,内蒙古,牙克石,022150 |
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| 摘 要： | 目的：评价国产紫杉醇联合卡铂治疗晚期非小细胞肺癌的临床疗效。方法：30例晚期非小细胞肺癌患者应用紫杉醇135mg／m^23～5h静脉滴注，卡铂300～350mg／m^2静脉滴注，每3周重复，进行3～4周期。结果：总有效率45％，平均生存期9．6个月，1年生存率35％，主要毒副反应是骨髓抑制，轻度恶心、呕吐、关节肌肉酸痛，未见严重过敏反应。结论：国产紫杉醇联合卡铂治疗晚期非小细胞肺癌有效率高，不良反应可耐受。
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| 关 键 词： | 紫杉醇 卡铂 非小细胞肺癌 化学疗法 |
| 文章编号： | 1004-0951(2004)02-0086-02 |
Combined Treatment of Paclitaxel and Carboplation for Late Non-small Cell Lung Cancer |
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| Guan Qi,QU Hong-lan,TAO Li-yan,XIN Guo-xiang.Combined Treatment of Paclitaxel and Carboplation for Late Non-small Cell Lung Cancer[J].Inner Mongolia Medical Journal,2004,36(2):86-87. |
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| Authors: | Guan Qi QU Hong-lan TAO Li-yan XIN Guo-xiang |
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| Institution: | GUAN Qi,QU Hong-lan,TAO Li-yan,XIN Guo-xiangWT5BX |
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| Abstract: | HTSSObjective:To evaluate the efficacy of national paditaxel plus carboplation for late non-small cell lung cancer(NSCLC) .Methods:For 30 patients with late NSCLC,paclitaxel,135mg/m 2,int ravenous drip between 3 and 5 hours,carboplalion,300 to 350mg/m 2,intravenous d rip,every 3 weeks,the course was 9 to 12 weeks.Results:The total e ffective rate was 45%.The mean survival time was 9.6 months.The survival rate in 1 year was 35%.The major side effects were arrest of bone marrow,mild nausea and vomiting,aching pain in joint and muscle,non alleagic reaction.Conclusi on:Combined treatment of national paclitaxel and carboplation is effectiv e for late NSCLC,with tolerable side effect. |
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| Keywords: | Paclitaxel Carboplation Non-small cell cancer(NSCLC) Chemotherapy |
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