| 国产洛伐他汀治疗原发性高胆固醇血症临床观察 |
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| 引用本文： | 张彤 杜凤和. 国产洛伐他汀治疗原发性高胆固醇血症临床观察[J]. 首都医科大学学报, 1998, 19(4): 339-341 |
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| 作者姓名： | 张彤 杜凤和 |
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| 作者单位： | 首都医科大学附属北京天坛医院心内科 |
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| 摘 要： | 采用随机双盲对照实验，观察了国产洛伐他汀（ｌｏｖａｓｔａｔｉｎ）治疗原发性高胆固醇血症的效果。结果：服国产洛伐他汀第１、２个月血清总胆固醇（ＴＣ）、低密度脂蛋白胆固醇（ＬＤＬ Ｃ）较治疗前明显下降（Ｐ＜０．０１），与美国产洛伐他汀比较作用无显著差异（Ｐ＞０．０５），２组副作用均较轻。结果提示国产洛伐他汀治疗原发性高胆固醇血症疗效可靠，与美国产同类产品疗效相当。
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| 关 键 词： | 原发性高胆固醇血症；洛伐他汀；治疗结果 |
| 收稿时间： | 1997-12-21 |
The Effect of Chinese Lovastatin on Essential Hypercholesterolemia |
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| Zhang Tong,Du Fenghe,Zhang Jianfeng. The Effect of Chinese Lovastatin on Essential Hypercholesterolemia[J]. Journal of Capital Medical University, 1998, 19(4): 339-341 |
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| Authors: | Zhang Tong Du Fenghe Zhang Jianfeng |
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| Affiliation: | Zhang Tong,Du Fenghe,Zhang Jianfeng Department of Cardiology,Beijing Tiantan Hospital,Affiliate of Capital University of Medical Sciences |
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| Abstract: | Fifty-eight patients with essential hypercholesterolemia(TC≥5.98 mmol/L)were treated with Chinese lovastatin and American lovastatin(MSD)by means of randomized double blind placebo-controlled clinical trials. The results showed that Chinese lovastatin decreased TC, LDL-C in the same manner as American lovastatin(MSD)within 1～2 month. Both of them had mild side-effects. |
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| Keywords: | hypercholesterolemia lovastatin effect of treatment |
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