Relationship Between Certain Radiographic and Biologic Characteristics in Breast Cancer |
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| Authors: | A. von Rosen M. Wiege B. Tornberg L. Hellstr m L. Skoog A. Somell G. Auer |
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| Affiliation: | a Departments of Surgery, Radiology and Clinical Pathology, Sodersjukhuset, Stockholmb Department of Tumor Pathology, Karolinska Institutet and Karolinska Sjukhuset, Stockholm, Sweden |
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| Abstract: | The relationship between mammographic appearance of micro-calcifications and tumor stage, malignancy grade, estrogen receptor (ER) content and nuclear DNA pattern was studied in 92 mammary carcinomas. The results indicate that no complementary prognostic guidance can be obtained from the radiographic appearance of a tumor apart from a high probability of a spiculated cancer being ER-rich. The finding of a relatively high proportion of aneuploid and ER-poor carcinomas among tumors with microcalcifications indicates that this radiographic characteristic might be associated with increased growth potential. |
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| Keywords: | Breast neoplasms carcinoma mammography DNA estrogen receptor |
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