肺癌脑转移的显微手术治疗

目的:探讨肺癌脑转移的手术适应证、手术方法,提高对肺癌脑转移显微手术治疗价值的认识。方法:回顾性分析我院自1996～2005年间46例确诊的肺癌脑转移患者的临床资料,采用显微手术方法切除肿瘤,术后给予全脑放疗和化疗。结果:肿瘤全切除37例,占80.43%;肿瘤次全切除9例,占19.57%;无术中死亡。术后症状完全缓解27例,占58.48%;部分缓解10例,占21.74%;无变化5例,占10.87%;进展4例,占8.91%。随访3个月～24个月,24个月生存率12.82%。结论:显微手术治疗是治疗肺癌脑转移的有效手段,手术治疗后联合放疗及化疗能延长患者的生存期,提高生存质量。

Microsurgical treatment of lung cancer with brain metastases

Objective: To investigate the surgical indications and operative methods of lung cancer with brain metastases. To improve the clinical value of microsurgical treatment on the brain metastases. Methods: 46 cases of lung cancer with brain metastases in our department in 1996 to 2005 were analyzed retrospectively. The performed treatments were microsurgery, whole brain radiation therapy and chemotherapy after operation. Results: Among all the cases, 37 cases were total resection(80.43%), 9 cases near total resection(19.57%). No case died during operations. 27 cases completely relieved(58.48%), 10 cases partial relieved(21.74%), 5 cases were unimproved(10.87%), 4 cases aggravated(8.91%). Follow-up was performed from 3 to 24 months after operation. Survival rate was 12.82% in 24 months. Conclusion: The microsurgical treatment on the lung cancer with brain metastases are effective and reliable. Committed radiation therapy and chemotherapy after operation can prolong patient' survival period, and improve their life qualitie.