婴幼儿急性下呼吸道感染的病原学研究

目的探婴幼儿急性下呼吸道感染(ALRI)的病毒病原学.方法采用直接免疫荧光法检测2209例急性下呼吸道感染患儿呼吸道诱导痰中脱落纤毛柱状上皮细胞中的呼吸道合胞病毒、流感病毒A型及B型、副流感病毒l、2、3型、腺病毒.结果2209例ALRI患儿中,病毒感染阳性率46.22%,其中主要为呼吸道合胞病毒(RSV)感染,其次为流感病毒和副流感病毒.婴幼儿病毒性ALRI好发于冬春季节.结论病毒感染在本地区ALRI中占重要地位.RSV是冬春季节婴幼儿ALRI的主要病原体,其次是流感病毒和副流感病毒.

A Study on Etiology of Acute Lower Respiratory Tract Infections in Infants

Objective To explore the viral etiology of acute lower respiratory tract infection (ALRI) in infants. Methods The respiratory syncytial virus (RSV), influenza virus (IFV) A and B, parainfluenza virus (PIV) 1, 2 and 3 and adenovirus (ADV) were detected in 2209 infants with ALRI by direct immunofluorescence method. Results Among 2209 inpatients, 1021 cases were positive for respiratory tract virus (positive rate, 46.22%), of which 653 cases were RSV positive (positive rate, 63.8%) and 74 cases were IFV positive (positive rate, 7.24%). The infection of respiratory tract viruses occurred commonly in winter and spring. Conclusions Viral infection is the main cause for ALRI. RSV is the most common viral pathogen of ALRI, and PIV and IFV are less common.