| Oral Gd-DTPA as a negative gastrointestinal contrast agent in magnetic resonance cholangiopancreatography |
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| 引用本文： | 陈燕萍,张雪林,昌仁民,成官迅. Oral Gd-DTPA as a negative gastrointestinal contrast agent in magnetic resonance cholangiopancreatography[J]. 中国人民解放军军医大学学报, 2003, 18(5): 325-330 |
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| 作者姓名： | 陈燕萍 张雪林 昌仁民 成官迅 |
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| 作者单位： | Imaging Diagnostic Center，Nanfang Hospital，First Military Medical University，Guangzhou 510515，China，Imaging Diagnostic Center，Nanfang Hospital，First Military Medical University，Guangzhou 510515，China，Imaging Diagnostic Center，Nanfang Hospital，First Military Medical University，Guangzhou 510515，China，Imaging Diagnostic Center，Nanfang Hospital，First Military Medical University，Guangzhou 510515，China |
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| 摘 要： | Objective : To evaluate the value of oral Gd-DTPA as a negative contrast agent during magnetic resonance cholangiopancreatography (MRCP) to eliminate the high signals of the gastrointestinal tract. Methods: To select the optimal concentration of oral Gd-DTPA for MRCP, a phantom study was performed followed by clinical trial in 15 cases undergoing MRCP before and after oral Gd-DTPA (in a total volume of 250 ml 1:5 diluted Gd-DTPA, 1.488 g/L). MRCP images were acquired using two-dimensional single slice fast spin-echo ( SSTSE) sequence and half-Fourier acquisition single slice fast spin-echo (HASTE) sequence. Results: The phantom study showed that the 1:5 diluted oral Gd-DTPA was best in decreasing the signal intensity both in T2-weighted imaging (59. 5% ) and in HASTE sequence (82.45% ). The high signal intensity of the stomach and intestinal fluid was completely suppressed in all the cases. The depictions of the common bile duct and pancreatic duct were markedly improved by using the oral contrast agent
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| 关 键 词： | 磁共振胰胆管造影术 Gd-DTPA 胃 肠 |
Oral Gd-DTPA as a negative gastrointestinal contrast agent in magnetic resonance cholangiopancreatography |
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| CHEN Yan-ping ZHANG Xue-lim CHANG Ren-min CHENG Guan-xunImaging Diagnostic Center,Nanfang Hospital,First Military Medical University,Guangzhou ,China. Oral Gd-DTPA as a negative gastrointestinal contrast agent in magnetic resonance cholangiopancreatography[J]. Journal of Medical Colleges of PLA(China), 2003, 18(5): 325-330 |
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| Authors: | CHEN Yan-ping ZHANG Xue-lim CHANG Ren-min CHENG Guan-xunImaging Diagnostic Center Nanfang Hospital First Military Medical University Guangzhou China |
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| Affiliation: | CHEN Yan-ping ZHANG Xue-lim CHANG Ren-min CHENG Guan-xunImaging Diagnostic Center,Nanfang Hospital,First Military Medical University,Guangzhou 510515,China |
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| Abstract: | Objective : To evaluate the value of oral Gd-DTPA as a negative contrast agent during magnetic resonance cholangiopancreatography (MRCP) to eliminate the high signals of the gastrointestinal tract. Methods: To select the optimal concentration of oral Gd-DTPA for MRCP, a phantom study was performed followed by clinical trial in 15 cases undergoing MRCP before and after oral Gd-DTPA (in a total volume of 250 ml 1:5 diluted Gd-DTPA, 1.488 g/L). MRCP images were acquired using two-dimensional single slice fast spin-echo ( SSTSE) sequence and half-Fourier acquisition single slice fast spin-echo (HASTE) sequence. Results: The phantom study showed that the 1:5 diluted oral Gd-DTPA was best in decreasing the signal intensity both in T2-weighted imaging (59. 5% ) and in HASTE sequence (82.45% ). The high signal intensity of the stomach and intestinal fluid was completely suppressed in all the cases. The depictions of the common bile duct and pancreatic duct were markedly improved by using the oral contrast agent (P<0.05). Conclusion: Oral Gd-DTPA is effective and safe for eliminating the high signal of the gastrointestinal tract to improve the depiction of the biliary system by MRCP. |
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| Keywords: | magnetic resonance cholangiopancreatography oral contrast agent pancreaticobiliary system gadolini-um-DTPA |
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