| 铅对心肌酶、钠钾泵、钙镁泵活性以及肾素、血管紧张素Ⅱ活性影响探讨 |
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| 引用本文： | 邹和建,丁钺,徐麦玲,黄开莲,曹新莉. 铅对心肌酶、钠钾泵、钙镁泵活性以及肾素、血管紧张素Ⅱ活性影响探讨[J]. 中国工业医学杂志, 1994, 7(1): 7-9 |
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| 作者姓名： | 邹和建 丁钺 徐麦玲 黄开莲 曹新莉 |
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| 作者单位： | 上海医科大学附属华山医院职业病科 200040(邹和建，丁钺，徐麦玲，黄开莲)，上海医科大学附属华山医院职业病科 200040(曹新莉) |
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| 摘 要： | 本研究同时测定了铅作业组、非铅作业组两组对象红细胞钠-钾泵、钙-镁泵活性、血浆肾素活性、血管紧张素Ⅱ以及血清心肌酶CMB、CPK、LDH活性。结果发现两组间钠-钾汞、钙-镁泵活性以及血浆肾素活性、血管紧张素Ⅱ均无显著差异,但铅作业组CMB水平与血铅水平呈正相关,提示铅负荷增加情况下可能导致心肌细胞损伤。心肌细胞受损是铅作业工人心功能受损的可能机制之一。
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| 关 键 词： | 肾素 心肌酶 铅中毒 腺苷三磷酸酶 |
Effect of Lead on Serium Myocardial Enzymes, Plasma Renin Activity,Angiotension I, Ca~(2+)-Mg~(2+)-ATPase and Na~+-K~+-ATPase |
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| Zou Hejian,et al. Effect of Lead on Serium Myocardial Enzymes, Plasma Renin Activity,Angiotension I, Ca~(2+)-Mg~(2+)-ATPase and Na~+-K~+-ATPase[J]. Chinese Journal of Industrial Medicine, 1994, 7(1): 7-9 |
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| Authors: | Zou Hejian et al |
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| Abstract: | Measurements of serum myocardial enzyme, plasma renin activity, angiotension I, Ca2+-Mg2+-ATPase and Na+-K+-ATPase were performed on lead exposed workers and control subjects. The results showed that serum CMB, CPK, LDH, Ca2+-Mg2+ -ATPase, Na+-K+-ATPase, plasma renin activity and angiotension I for both groups were within normal limits, but a positive correlation was found between CMB and Pb-B .It denoted that the increasing of lead burden leads to more release of CNB from the myocardial cells and suggesed the existence of sligt myocardial damage. |
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| Keywords: | lead adenosine triphosphatase renin myocardial enzymes |
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