MRI分区定位联合经直肠B超引导前列腺穿刺活检在前列腺癌诊断 中的应用

目的 探讨MRI分区定位联合经直肠B超引导前列腺穿刺活检在前列腺癌诊断中的临床应用价值。方法 对50例临床PSA升高患者行核磁检查并进行12分区，分区与经直肠B超引导穿刺方向、区域一致，然后行经直肠前列腺穿刺术，即在传统穿刺的基础上，增加MRI分区异常区域的穿刺点。统计传统穿刺和传统穿刺联合可疑分区穿刺的前列腺癌阳性率。 结果 传统穿刺和传统穿刺联合可疑分区穿刺的阳性率分别为0.36和0.42，并发症血尿5例，大便带血13例，发热1例，无其他严重并发症。结论 MRI分区有助于发现可疑前列腺癌区域，为TURS引导下经直肠前列腺穿刺提供目标，提高前列腺癌穿刺阳性率，联合MRI分区定位经直肠B超引导前列腺穿刺活检对前列腺癌的早期诊断具有很高的临床价值。

Prostate biopsy guided by transrectal ultrasound combined with MRI compartmental localization in diagnosis of prostate cancer

Objective To explore the value of prostate biopsy under the guidance of transrectal ultrasound and compartmental localization of MRI in the diagnosis of prostate cancer. Methods Fifty patients with elevated prostate specific antigen levels were recruited. All patients underwent MRI scan before biopsy. The prostate was divided into 12 compartments under MRI scan. Systematic 12-samples needle biopsy was performed and additional biopsy was added for suspected compartment. According to histopathology, the prostate cancer detection rate of systematic 12-samples needle biopsy and that of systematic biopsy with added punctures of suspected compartment were analyzed. Results Prostate cancer detection rate of systematic 12-samples needle biopsy and that of systematic biopsy with added punctures of suspected compartment were 0.36 and 0.42 respectively. Five cases had hematuria, 13 cases had bloody stools, and 1 cases had fever. Conclusion Transrectal ultrasound guided with compartmental localization of MRI prostate biopsy can significantly improve the positive biopsy rate and has higher clinical value in early diagnosis of prostate cancer.