| 老年胰岛素抵抗与下肢动脉病变的相关性 |
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| 引用本文： | 吴标良,王民登,韦华,何明杰.老年胰岛素抵抗与下肢动脉病变的相关性[J].中国老年学杂志,2011,31(13). |
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| 作者姓名： | 吴标良 王民登 韦华 何明杰 |
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| 作者单位： | 右江民族医学院附属医院内分泌科,广西,百色,533000 |
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| 基金项目： | 广西教育厅科研项目基金 |
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| 摘 要： | 目的 探讨老年胰岛素抵抗(IR)与下肢动脉病变(PAD)的相关性.方法 100例新诊断老年2型糖尿病(T2DM)患者,采用稳态模型计算胰岛素抵抗指数(HOMA-IR),并根据HOMA-IR值分3组,通过测量踝臂指数(ABI)评价患者PAD情况,观察IR与PAD的相关性.结果 随着HOMA-IR的升高,收缩压(SBP)、低密度脂蛋白胆固醇(LDL-C)、糖化血红蛋白(HbA1c)逐渐升高,ABI逐渐降低(F=9.115、21.954、24.9、7.524,P＜ 0.01);HOMA-IR与ABI呈负相关(r=-0.352,P＜0.01),与SBP、LDL-C、餐后2小时血糖(2 h PG)、HbA1c呈正相关(r=0.346、0.532、0.222、0.534、0.376,P＜0.05或P＜0.01).结论 老年IR与PAD有强相关性,是发生PAD的高危因素.
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| 关 键 词： | 老年 胰岛素抵抗 下肢动脉病变 2型糖尿病 |
Correlation between insulin resistance and peripheral arterial disease in the aged |
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| WU Biao-Liang,WANG Min-Deng,WEI Hua,et al..Correlation between insulin resistance and peripheral arterial disease in the aged[J].Chinese Journal of Gerontology,2011,31(13). |
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| Authors: | WU Biao-Liang WANG Min-Deng WEI Hua |
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| Institution: | WU Biao-Liang,WANG Min-Deng,WEI Hua,et al.Department of Endocrine,Affiliated Hospital of Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China |
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| Abstract: | Objective To study correlation between insulin resistance(IR) and peripheral arteria disease(PAD) in the aged.Methods 100 newly diagnosed aged type 2 diabetes mellitus(T2DM) patients were divided into three groups according to the homeostasis model assessment insulin resistance index(HOMA-IR).PAD was evaluated by ankle-brachial index(ABI) and correlation between IR and PAD in the aged was studied.Results With the HOMA-IR increasing,the systolic blood pressure(SBP),low-density lipoprotein cholesterol(LDL-C) ... |
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| Keywords: | Aged Insulin Resistance Peripheral Arterial Disease Type 2 diabetes mellitus |
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