冠心病患者血清尿酸、C反应蛋白及尿微量清蛋白的相关性分析

目的探讨冠心病（CHD）患者血清尿酸、C反应蛋白及尿微量清蛋白的关系。方法测定94例CHD患者及102例健康体检者血清UA、CRP、mAlb与血脂并进行相关性分析。结果 CHD两组血清UA：AMI组（471.7±67.3）μmol/L,非AMI组（416.2±40.8）μmol/L,均显著高于健康对照组（249.6±46.5）μmol/L（P〈0.001）;CHD两组血清CRP：AMI组（58.3±13.4）mg/L,非AMI组（21.7±9.8）mg/L,均显著高于健康对照组（3.9±1.2）mg/L（P〈0.001）;CHD两组血清mAlb：AMI组（83.18±12.46）mg/L,非AMI组（47.17±10.73）mg/L,均显著高于健康对照组（6.64±3.56）（P〈0.001）;而HDL-C：AMI组（0.97±0.33）mmol/L,非AMI组（1.03±0.22）mmol/L均显著低于健康对照组（1.55±0.40）mmol/L（P〈0.05）。结论 CHD患者血清UA、CRP和mAlb水平明显增高,而且呈一定相关性。

Correlation Analysis of Serum Uric Acid, C-reactive Protein and Urine Albumin of Patients with Coronary Heart Disease

Objective To discuss the relation of serum uric acid,C-reactive protein and urine albumin of patients with coronary heart disease.Methods To mesure UA,CRP,mAlb and blood lipid of 94 patients with coronary heart disease and 102 healthy individuals.Results In the patients with coronary heart disease of the two groups,UA in AMI group was（471.7 ± 67.3） μmol/L,UA in non-AMI group was（416.2 ± 40.8） μmol/L.UA of the two groups were significantly higher than healthy control group（249.6 ± 46.5） μmol/L（P 0.001）.CRP in AMI group was（58.3 ± 13.4） mg/L,CRP in non-AMI group was（21.7 ± 9.8） mg/L.CRP of the two groups were significantly higher than healthy control group（3.9 ± 1.2） mgl/L（P 0.001）.mAlb in AMI group was（83.18 ± 12.46） mg/L,mAlb in non-AMI group was（47.17 ± 10.73） mg/L.mAlb of the two groups were significantly higher than healthy control group（6.64 ± 3.56） mg/L（P 0.001）.However,HDL-C in AMI group（0.97 ± 0.33） mmol/L and non-AMI group（1.03 ± 0.22） mmol/L were significantly lower than healthy control group（1.55 ± 0.40） mmol/L（P 0.05）.Conclusion UA,CRP and mAlb levels of CHD patients increase significantly,which have some correlation.