抗CCP抗体、RA33抗体和IgG－Rf因子在类风湿性关节炎中的诊断价值

目的：探讨抗环瓜氨酸肽抗体（抗-CCP）、RA33抗体和类风湿因子IgG-Rf对类风湿性关节炎（RA）的临床诊断价值。方法：选择RA患者65例、非BA患者50例健康体检者50例，应用酶联免疫吸附试验（ELISA）检测抗CCP抗体、抗RA33抗体，应用免疫透射比浊法检测IgG-Rf。结果：抗CCP抗体、RA33抗体和IgG-Rf对RA诊断的敏感性分别为58．5％、33．9％、75．4％；特异性分别为98．O％、97．0％、81．0％。结论：抗CCP抗体、RA33抗体对RA诊断的特异性优于RF（P〈0．05），可作为RA诊断的特异性血清学指标；RF与抗CCP抗体和RA33抗体同时检测用于RA的诊断是临床的最佳选择。

Resistance to CCP antibody, RA33 antibodies and Rf factor in - IgG rheumatoid arthritis diagnosis of value

Objective： to study the resistance to ring the melon acid peptide antibody （CCP）, RA33 fight- antibody and rheumatoid factor- to Rf IgG rheumatoid arthritis （RA） the diagnostic value. Method： choose RA65 patients, the RA patients 50 cases the healthy check - up 50 cases, application ELISA test （ELISA） detection of CCP antibody, the RA33 antibody, application of immune transmission than turbidity method to detect IgG-Rf. Results： the CCP antibody, RA33 antibodies and IgG-Rf. The diagnosis of ILk sensitivity of 58.5%, 33.9% and 75.4% respectively; Specificity of 98.0%, 97.0% and 81.0% respectively. Conclusion： the CCP antibody, RA33 antibodies to the specificity of diagnosis RA than RF （P 〈 0. （15）, can be used as RA specificity of diagnosis; serological index RF of CCP antibodies and RA33 antibody and tested in RA diagnosis is clinical best choice.