| 中枢性性早熟患儿5种骨龄测定方法的比较研究 |
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| 引用本文： | 白万晶,宁刚,曲海波,吴康敏,向承发. 中枢性性早熟患儿5种骨龄测定方法的比较研究[J]. 中国医学文摘(儿科学), 2011, 0(2) |
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| 作者姓名： | 白万晶 宁刚 曲海波 吴康敏 向承发 |
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| 作者单位： | 四川大学华西第二医院放射科;四川大学华西第二医院儿科; |
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| 摘 要： | 目的探讨CHN法、TW2法中日英3种标准、TW3法5种骨龄测定方法对中枢性性早熟(CPP)患儿的诊断价值及正常值临界点的确定。方法由两名医师采用盲法回顾性分析CPP患儿61例(病例组),与每一个CPP患儿性别相同,年龄、身高、体质量基本一致的同期体检者61例、8岁以后出现乳房发育的女童6例(均为对照组)治疗前左手腕部X线片,用CHN法、TW2法中英日3种标准和TW3法进行骨龄判定,计算骨龄与年龄的差值,用SPSS13.0统计软件进行受试者工作特征(ROC)分析。结果 (1)两名医师骨龄测定结果的Kappa值为0.776(u=16.128,P<0.05);(2)5种骨龄测定方法的ROC曲线下面积分别为:CHN法0.921±0.024,95%可信区间为0.875～0.967;TW2法中国南方人标准为0.947±0.019(0.910～0.983);TW2法日本人标准为0.937±0.023(0.892～0.982);TW2法英国人标准为0.931±0.022(0.888～0.975);TW3骨龄测定法为0.924±0.023(0.879～0.969);5种方法的诊断价值差异无统计学意义(Z=0.85,P>0.05...
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| 关 键 词： | 性早熟 骨龄测定 发育 骨骼 儿童 |
Comparison research on five ways of skeletal age determination in children with central precocious puberty |
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| BAI Wan-jing,NING Gang,QU Hai-bo,et al.. Comparison research on five ways of skeletal age determination in children with central precocious puberty[J]. Chinese Medical Digest(Pediatrics), 2011, 0(2) |
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| Authors: | BAI Wan-jing NING Gang QU Hai-bo et al. |
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| Affiliation: | BAI Wan-jing,NING Gang,QU Hai-bo,et al.Department of Radiology,West China Second Hospital,Sichuan University,Chengdu 610041,China |
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| Abstract: | Objective To discuss the diagnostic values of CHN method,Chinese,Japanese and English standards of TW2 method,and TW3 method in skeletal age(SA)determination in children with central precocious puberty(CPP),then to comform the normal thresholds.Methods Patient group:61 children with complete information.Control group had 67 children:(1)61 cases were normal children,whose sex,age,height and weitht were similar to the patient group;(2)6 cases were girls whose breasts developed after 8 years old.Left hand-wris... |
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| Keywords: | Sexual maturation Skeletal age determination Deve lopment Skeleton Children |
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