利多卡因凝胶联合曲马多防治尿管相关膀胱刺激症的效果观察

目的：探讨联合使用利多卡因凝胶局部麻醉导尿及静脉注射曲马多对全身麻醉患者尿管相关膀胱刺激症的影响。方法：选择120例男性胸、腹部手术患者,将其随机等分为试验组和对照组。试验组全身麻醉气管插管结束后在利多卡因凝胶局部麻醉下导尿,术毕予小剂量曲马多静脉注射。对照组在全身麻醉后行常规导尿术,术毕予相同体积的生理盐水。比较两组患者膀胱刺激症的发生程度。结果：与对照组比较,试验组患者膀胱刺激症发生程度明显减轻（P〈0.05）。试验组患者中有1例使用了曲马多自诉恶心,未呕吐。对照组患者没有出现明显的恶心呕吐等不良反应。结论：利多卡因凝胶局部麻醉联合静脉注射曲马多能降低全身麻醉患者尿管相关膀胱刺激症的发生率,减轻患者的苏醒期躁动。

The effect of lidocaine and tramadol on prevention and treatment catheter-related bladder discomfort

Objective：To observe the effect of lidocaine gel catheterization and tramadol on male patients of catheter-related bladder discomfort（CRBD）undergoing general anesthesia.Methods：120 male patients undergoing thoracic or abdomen surgeries were selected and randomly divided into experimental group and control group.All patients received the same general anesthesia.Urethral catheterization performed under topical anesthesia with lidocaine gel under general anesthesia in experimental group and with liquid paraffin in control group.At the end of the surgery,tramadol of 1mg /kg were given intravenous in experimental group and saline were given in control group.Incidence of catheter-related bladder discomfort were compared.Results：The incidence and severity of CRBD were significantly decreased in experimental group compared with those in control group（P〈0.05）.Conclusion：Lidocaine gel topical anesthesia with low-dose tramadol intravenous injection could effectively prevent catheter-related bladder discomfort after urethral catheterization in patients undergoing general anesthesia,thus increase the degree of comfort during recovery of anesthesia.