CD4+ and CD8+ T-lymphocyte subsets in Zambian children |
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| Authors: | Ndhlovu Zaza Ryon Judith J Griffin Diane E Monze Mwaka Kasolo Francis Moss William J |
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| Institution: | Virology Laboratory, University Teaching Hospital, Lusaka, Zambia. |
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| Abstract: | Age-related changes in lymphocyte subsets in HIV-uninfected Zambian children are described. The total lymphocyte count and numbers of CD4+ and CD8+ T-lymphocytes declined with increasing age, while the percentage of CD4+ and CD8+ T-lymphocytes changed little during childhood. Girls between the ages of 12 and 71 months had a higher percentage of CD4+ T-lymphocytes and a higher CD4:CD8 ratio than did boys of a similar age. |
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